- 中文名称：
-
- 中文别名：
- 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol,hydrate
- 英文名称：
- Ethanol,2,2'-[(4,5-diphenyl-2-oxazolyl)imino]bis-, monohydrate (9CI)
- 英文别名：
- 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol,hydrate;
S 222;
Diethamphenazol monohydrate;
Ageroplas;
Ditazol monohydrate
- CAS No.：
- 63867-52-7
- 分 子 式：
-
C19H20N2O3.H2O
- 分 子 量：
- 342.43
- 精确分子量：
- 342.15800
- PSA：
- 78.96000
- 安全术语：
- Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An anti-inflammatory agent. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 沸点：
- 505.5ºC at 760 mmHg
- 闪点：
- 259.5ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KK7400000
- CHEMICAL NAME :
- Ethanol, 2,2'-((4,5-diphenyl-2-oxazolyl)imino)di-,
monohydrate
- CAS REGISTRY NUMBER :
- 63867-52-7
- LAST UPDATED :
- 199007
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H20-N2-O3.H2-O
- MOLECULAR WEIGHT :
- 342.43
- WISWESSER LINE NOTATION :
- T5N COJ BN2Q2Q DR& ER &QH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11380 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 23,1283,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7770 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 23,1283,1973
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Behavioral - analgesia
Biochemical - Metabolism (Intermediary) - effect on inflammation or
mediation of inflammation
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 11,1092,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3390 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 23,1283,1973
