- 中文名称：
-
- 中文别名：
-
- 英文名称：
- 6H-Purin-6-one,2-amino-1,9-dihydro-, 7-oxide
- 英文别名：
- Guanine, N-7-oxide;
guanine 7-oxide;
2-Amino-3,9-dihydro-6H-purin-6-one 7-oxide;
2-Amino-1,9-dihydro-6H-purin-6-one 7-oxide;
Antibiotic 3780
- CAS No.：
- 5227-68-9
- 分 子 式：
-
C5H5N5O2
- 分 子 量：
- 167.15
- 精确分子量：
- 167.04400
- PSA：
- 113.28000
- InChI：
- The Key: VWMKKTYDXHGESB-UHFFFAOYSA-N3
- 安全术语：
- Poison by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits very toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 2.31g/cm3
- 沸点：
- 603.8ºC at 760mmHg
- 闪点：
- 319ºC
- 折射率：
- 2.046
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MF8585000
- CHEMICAL NAME :
- Guanine 7-N-oxide
- CAS REGISTRY NUMBER :
- 5227-68-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C5-H5-N5-O2
- MOLECULAR WEIGHT :
- 167.15
- WISWESSER LINE NOTATION :
- T56 BM DN FVM INJ DO HZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72.
Discontinued. Volume(issue)/page/year: 3,181,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 38,972,1985
** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 390 mg/kg/26W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
27,925,1967
海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
