N,N-二甲基-10H-吩噻嗪-10-乙胺单盐酸盐
- 中文名称：
- N,N-二甲基-10H-吩噻嗪-10-乙胺单盐酸盐
- 中文别名：
-
- 英文名称：
- 10H-Phenothiazine-10-ethanamine,N,N-dimethyl-, hydrochloride (1:1)
- 英文别名：
- N,N-Dimethyl-2-(10H-phenothiazin-10-yl)ethanamine hydrochloride;
N,N-dimethyl-2-phenothiazin-10-ylethanamine,hydrochloride
- CAS No.：
- 5934-20-3
- 分 子 式：
-
C16H18N2S.ClH
- 分 子 量：
- 306.88
- 精确分子量：
- 306.09600
- PSA：
- 31.78000
- EINECS：
- 227-685-0
- InChI：
- The Key: CKIPCLCBYTWUEZ-UHFFFAOYSA-N3
- 安全术语：
- Poison by intraperitoneal and subcutaneous routes. An antihistamine. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl.
- 分子结构式：
-
- SDS：
- 查看
N,N-二甲基-10H-吩噻嗪-10-乙胺单盐酸盐 物化性质
- 沸点：
- 396.1ºC at 760 mmHg
- 闪点：
- 193.3ºC
N,N-二甲基-10H-吩噻嗪-10-乙胺单盐酸盐 安全信息
N,N-二甲基-10H-吩噻嗪-10-乙胺单盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SO5425000
- CHEMICAL NAME :
- Phenothiazine, 10-(2-(dimethylamino)ethyl)-,
hydrochloride
- CAS REGISTRY NUMBER :
- 5934-20-3
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C16-H18-N2-S.Cl-H
- MOLECULAR WEIGHT :
- 306.88
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B2N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 20(1),23,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 90,224,1947
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 224 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Skin and Appendages - hair
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon
Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year:
54,33,1958
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 20(1),23,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 174 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 3,328,1953
N,N-二甲基-10H-吩噻嗪-10-乙胺单盐酸盐 海关数据
中国海关编码：2934300000
- 概述：
- 2934300000. 含一个吩噻嗪环系的化合物(吩噻嗪环系不论是否氢化,化合物未经进一步稠合的 ). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
