- 中文名称：
-
- 中文别名：
- N,N-diethyl-2-[2-(2-methyl-5-phenylpyrrol-1-yl)phenoxy]ethanamine,hydrochloride
- 英文名称：
- Ethanamine,N,N-diethyl-2-[2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy]-, hydrochloride(1:1)
- 英文别名：
- N,N-diethyl-2-[2-(2-methyl-5-phenylpyrrol-1-yl)phenoxy]ethanamine,hydrochloride;
1-[2-(2-Diaethylamino-aethoxy)-phenyl]-2-methyl-5-phenyl-pyrrol;
1-(2-<2-Diethylamino-ethoxy>-phenyl)-2-methyl-5-phenyl-pyrrol;
Leiopyrrole;
Pyrrole,1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-phenyl;
Leiopirrol [INN-Spanish];
Ethanamine,N,N-diethyl-2-(2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy);
Leiopirrol;
1-[2-(2-Diaethylamino-aethoxy)-phenyl]-2-methyl-5-phenyl-pyrrol,Hydrochlorid;
1-[2-(2-diethylamino-ethoxy)-phenyl]-2-methyl-5-phenyl-pyrrole,hydrochloride;
Leiopyrrolum [INN-Latin];
1-(o-(2-(Diethylamino)ethoxy)phenyl)-2-methyl-5-phenylpyrrole;
2-Methyl-5-phenyl-1-<2-(2-diethylamino-ethoxy)-phenyl>-pyrrol;
1-[2-(2-diethylamino-ethoxy)-phenyl]-2-methyl-5-phenyl-pyrrole;
DV 714;
Leioplegil
- CAS No.：
- 14435-78-0
- 分 子 式：
-
C23H28N2O.ClH
- 分 子 量：
- 348.4812
- 精确分子量：
- 384.19700
- PSA：
- 17.40000
- InChI：
- The Key: JTOGCNWNXIHUHX-UHFFFAOYSA-N3
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 1.01g/cm3
- 沸点：
- 497.9ºC at 760mmHg
- 闪点：
- 254.9ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UX9465070
- CHEMICAL NAME :
- Pyrrole,
1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-pheny
l-, monohydrochloride
- CAS REGISTRY NUMBER :
- 14435-78-0
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C23-H28-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 384.99
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 475 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil,
France) V.1- 1943- Volume(issue)/page/year: 19,753,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
