N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐
- 中文名称：
- N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐
- 中文别名：
- N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐
- 英文名称：
- Benzeneethanamine,N-(3-chloropropyl)-a-methyl-, hydrochloride (1:1)
- 英文别名：
- N-(3-chloropropyl)-1-phenylpropan-2-amine,hydrochloride;
Mefenorex HCl;
Doracil;
Pondinil;
EINECS 226-985-9;
Rondimen;
Ro 4-5282;
N-Chloropropylamphetamine hydrochloride;
R 4-5282;
Mefenorex hydrochloride
- CAS No.：
- 5586-87-8
- 分 子 式：
-
C12H18ClN.ClH
- 分 子 量：
- 248.22
- 精确分子量：
- 247.08900
- PSA：
- 12.03000
- EINECS：
- 226-985-9
- 安全术语：
- Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and Cl−.
- 分子结构式：
-
- SDS：
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N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐 物化性质
- 沸点：
- 305.1ºC at 760mmHg
- 闪点：
- 138.3ºC
N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH2100000
- CHEMICAL NAME :
- Phenethylamine, N-(3-chloropropyl)-alpha-methyl-,
hydrochloride
- CAS REGISTRY NUMBER :
- 5586-87-8
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C12-H18-Cl-N.Cl-H
- MOLECULAR WEIGHT :
- 248.22
- WISWESSER LINE NOTATION :
- G3MY1&1R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 410 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 19,748,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 35 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 19,748,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 19,748,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 144 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 19,748,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 49 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 236 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972
