特非那定,50679-08-8，生产厂家，价格-洛克化工网移动版

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基本信息

制备方法及用途

物化性质

安全信息

毒理性

MSDS

海关数据

结构与计算化学

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下游产品

特非那定

中文名称：: 特非那定

中文别名：: 特非那定;
Α-[4-(1,1-二甲基乙基)苯基]-4-(羟基二苯甲基)-1-哌啶丁醇;
叔哌丁醇;
Α-[4-叔丁基苯基]-4-(羟基二苯基甲基)-1-哌啶丁醇;
α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol;
alpha-[4-叔丁基苯基]-4-(羟基二苯基甲基)-1-哌啶丁醇

英文名称：: 1-Piperidinebutanol, a-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-

英文别名：: 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol;
Teldane;
Allerplus;
Terfenadine;
[3H]-Terfenadine;
Teldanex;
Ternadin;
Triludan;
terfenadine;
Seldane;
Terfenadina;
Aldaban;
Terdin;
[14C]-Terfenadine

CAS No.：: 50679-08-8

分子式：: C₃₂H₄₁NO₂

分子量：: 471.67

精确分子量：: 471.31400

PSA：: 43.70000

MDL：: MFCD00079622

EINECS：: 256-710-8

InChI：: The Key: GUGOEEXESWIERI-UHFFFAOYSA-N3

危险品标志：

风险术语：

安全术语：: S24/25;

分子结构式：

SDS：: 查看

特非那定制备方法及用途

制备方法

α，α-二苯基-4-哌啶基甲醇(107g，0.4mo1)(其制备参见McCarty F J，et a1．J Org Chem，1961，26：4084)、1-[4-(1，1-二甲基乙基)苯基]-4-氯-1-丁酮(105g，0.44mo1)(其制备参见Van de Westerign C，et a1．Ind chim beige，1960,25：1073；CA 55：6428b．1961)、碳酸氢钾(70g，0.7mo1)和0.1g碘化钾在600ml甲苯中，搅拌回流60h。反应液乘热过滤，滤液冷却后和过量的氯化氢乙醚溶液作用。过滤收集产生的沉淀，用甲醇-异丙醇(5：12)重结晶，得78.4g化合物(I)，收率24%。化合物(I)(60g，0.12mo1)溶于1.2 L甲醇，加入氢氧化钾的甲醇溶液至反应液呈碱性。然后冷至01；，在搅拌下分批加入硼氢化钾(5g，0.132mo1)。移去冷却，搅拌1h。在蒸汽浴上减压浓缩，得到固体剩余物。该固体用水洗后，以丙酮重结晶2次，得34.4g特非那定，收率61.5%。

合成制备方法

α，α-二苯基-4-哌啶基甲醇(107g，0.4mo1)(其制备参见McCarty F J，et a1．J Org Chem，1961，26：4084)、1-[4-(1，1-二甲基乙基)苯基]-4-氯-1-丁酮(105g，0.44mo1)(其制备参见Van de Westerign C，et a1．Ind chim beige，1960,25：1073；CA 55：6428b．1961)、碳酸氢钾(70g，0.7mo1)和0.1g碘化钾在600ml甲苯中，搅拌回流60h。反应液乘热过滤，滤液冷却后和过量的氯化氢乙醚溶液作用。过滤收集产生的沉淀，用甲醇-异丙醇(5：12)重结晶，得78.4g化合物(I)，收率24%。
化合物(I)(60g，0.12mo1)溶于1.2 L甲醇，加入氢氧化钾的甲醇溶液至反应液呈碱性。然后冷至01；，在搅拌下分批加入硼氢化钾(5g，0.132mo1)。移去冷却，搅拌1h。在蒸汽浴上减压浓缩，得到固体剩余物。该固体用水洗后，以丙酮重结晶2次，得34.4g特非那定，收率61.5%。

用途简介

新型抗组胺药，有特异的外周H1受体拮抗作用，且没有抗5-羟色胺、抗胆碱能和抗肾上腺素能的作用。适用于季节性过敏性鼻炎(花粉症)、常年性过敏鼻炎、急慢性荨麻疹等的治疗。

用途

新型抗组胺药，有特异的外周H1受体拮抗作用，且没有抗5-羟色胺、抗胆碱能和抗肾上腺素能的作用。适用于季节性过敏性鼻炎(花粉症)、常年性过敏鼻炎、急慢性荨麻疹等的治疗。

特非那定物化性质

外观与性状：
固体结晶粉末

密度：
1.088 g/cm3

熔点：
145-152 °C

沸点：
626.8ºC at 760 mmHg

闪点：
306.9ºC

水溶解性：
0.001 g/100 mL (30 ºC)

存储条件/存储方法：

密封、在2 ºC -8 ºC下保存

稳定性相关：

如果遵照规格使用和储存则不会分解，未有已知危险反应

其它信息：

1.       性状：粉末
2.       密度（g/mL,25ºC）：未确定
3.       相对蒸汽密度（g/mL,空气=1）：未确定
4.       熔点（ºC）：145-152
5.       沸点（ºC）：未确定
6.       沸点（ºC，46mm hg）：未确定
7.       折射率：未确定
8.       闪点（°C）：未确定
9.       比旋光度（ºC）：未确定
10.    自燃点或引燃温度（ºC）：未确定
11.    蒸气压（kPa,20ºC）：未确定
12.    饱和蒸气压（kPa,60ºC）：未确定
13.    燃烧热（KJ/mol）：未确定
14.    临界温度（ºC）：未确定
15.    临界压力（KPa）：未确定
16.    油水（辛醇/水）分配系数的对数值：未确定
17.    爆炸上限（%,V/V）：未确定
18.    爆炸下限（%,V/V）：未确定
19.    溶解性：能溶于水的

特非那定安全信息

海关代码：
2933399090

WGK_Germany：
2
德国有关水污染物质的分类清单

安全说明：
S24/25

RTECS号：
TM4969000

特非那定毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM4969000

CHEMICAL NAME :
1-Piperidinebutanol, alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydipheny lmethyl)-

CAS REGISTRY NUMBER :
50679-08-8

LAST UPDATED :
199801

DATA ITEMS CITED :
21

MOLECULAR FORMULA :
C32-H41-N-O2

MOLECULAR WEIGHT :
471.74

WISWESSER LINE NOTATION :
T6NTJ A3YQR DX1&1&1& DXQR&R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Human

DOSE/DURATION :
857 ug/kg

TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - alteration of operant conditioning Behavioral - changes in psychophysiological tests

REFERENCE :
EJCPAS European Journal of Clinical Pharmacology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.3- 1970- Volume(issue)/page/year: 47,331,1994

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Human - man

DOSE/DURATION :
36 mg/kg/3W-I

TOXIC EFFECTS :
Liver - jaundice, cholestatic Liver - liver function tests impaired

REFERENCE :
LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 348,552,1996

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Human - child

DOSE/DURATION :
3 mg/kg

REFERENCE :
BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 293,536,1986

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Human - man

DOSE/DURATION :
156 mg/kg/13W-I

TOXIC EFFECTS :
Skin and Appendages - hair

REFERENCE :
BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 291,940,1985

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Human - man

DOSE/DURATION :
857 ug/kg

REFERENCE :
BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 293,536,1986

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Human - woman

DOSE/DURATION :
1200 ug/kg

REFERENCE :
BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 293,536,1986

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Human - woman

DOSE/DURATION :
190 mg/kg/23W-I

TOXIC EFFECTS :
Behavioral - muscle weakness Liver - jaundice, other or unclassified Liver - liver function tests impaired

REFERENCE :
AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 103,634,1985

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
5 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

REFERENCE :
PHINDQ Pharmacy International. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1980- Volume(issue)/page/year: 4,252,1983

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Intraperitoneal

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
154 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Subcutaneous

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
>1250 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
5 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

REFERENCE :
PHINDQ Pharmacy International. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1980- Volume(issue)/page/year: 4,252,1983

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Intraperitoneal

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
246 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 21,319,1990

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Subcutaneous

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
>4500 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,707,1990

TYPE OF TEST :
LD - Lethal dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Mammal - dog

DOSE/DURATION :
>1500 mg/kg

TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting

REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 31,845,1986

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - guinea pig

DOSE/DURATION :
>2 gm/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

REFERENCE :
MEIEDD Merck Index. (Merck & Co., Inc., Rahway, NJ 07065) 10th ed. 1983. For publisher information, see 85KYAH. Volume(issue)/page/year: 11,1443,1989

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Intraperitoneal

SPECIES OBSERVED :
Mammal - species unspecified

DOSE/DURATION :
43 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 38,2472,1995 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Mammal - dog

DOSE/DURATION :
3600 mg/kg/30D-C

TOXIC EFFECTS :
Behavioral - food intake (animal) Lungs, Thorax, or Respiration - other changes Liver - changes in liver weight

REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 31,845,1986 ** REPRODUCTIVE DATA **

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
8400 mg/kg

SEX/DURATION :
female 14 day(s) pre-mating female 1-14 day(s) after conception

TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,1179,1982

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
8550 mg/kg

SEX/DURATION :
female 14 day(s) pre-mating - 21 day(s) post-birth

TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,1179,1982

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
17100 mg/kg

SEX/DURATION :
female 14 day(s) pre-mating - 21 day(s) post-birth

TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)

REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,1179,1982

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

DOSE :
1100 mg/kg

SEX/DURATION :
female 7-17 day(s) after conception

TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Effects on Newborn - other postnatal measures or effects

REFERENCE :
JZKEDZ Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. (Jikken Dobutsu Chuo Kenkyusho, 1433 Nogawa, Takatsu-ku, Kawasaki 211, Japan) V.1- 1975- Volume(issue)/page/year: 13,1,1987

生态数据：

对水是稍微有危害的不要让未稀释或大量的产品接触地下水、水道或者污水系统，若无政府许可，勿将材料排入周围环境

特非那定 MSDS

Name: Terfenadine Material Safety Data Sheet

Synonym:

CAS: 50679-08-8

Section 1 - Chemical Product MSDS Name:Terfenadine Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS# Chemical Name content EINECS#

50679-08-8 Terfenadine 256-710-8

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 50679-08-8: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystalline powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 146-148 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 0.001 g/100 ml H2O (30C)
Specific Gravity/Density:
Molecular Formula: C32H41NO2
Molecular Weight: 471.2925

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 50679-08-8: TM4969000 LD50/LC50:
CAS# 50679-08-8: Oral, mouse: LD50 = 5 gm/kg; Oral, rat: LD50 = 5 gm/kg.
Carcinogenicity:
Terfenadine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 50679-08-8: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 50679-08-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 50679-08-8 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

特非那定海关数据

中国海关编码：2933399090

概述：

2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

申报要素：

品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

摘要/Summary：

2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

特非那定分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值（XlogP）:6.6
2.氢键供体数量:2
3.氢键受体数量:3
4.可旋转化学键数量:9
5.互变异构体数量:无
6.拓扑分子极性表面积43.7
7.重原子数量:35
8.表面电荷:0
9.复杂度:582
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:1
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:1

特非那定上游产品

1-(4-(tert-butyl)phenyl)prop-2-en-1-ol 氮杂环醇 4'-叔-丁基-4-[4-(羟基二苯甲基)哌啶]苯丁酮

特非那定下游产品

非索非那定 4'-叔-丁基-4-[4-(羟基二苯甲基)哌啶]苯丁酮

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上海吉至生化科技有限公司

特非那定
联系人：江珊
电  话：021-57520831
手  机：15316869680
Cas号：50679-08-8
包装：50mgea
纯度：HPLC≥98%
价格：138.0元
上海源叶生物科技有限公司

50679-08-8
联系人：Yuki
电  话：021-61845781
手  机：13585604150
Cas号：50679-08-8
包装：50mg
纯度：HPLC≥99%
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湖北魏氏化学试剂股份有限公司

特非那定（不合格）
联系人：张经理
电  话：027-59102966
手  机：18717199209
Cas号：50679-08-8
包装：25/纸板桶kg
纯度：99%
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特非那定
联系人：黄
电  话：027-50662354
手  机：13264726139
Cas号：50679-08-8
包装：100kg,200kg
纯度：99%
价格：1.0元 - 1.0元
湖北江民泰华化工有限公司

特非那定
联系人：张经理
电  话：13396038321
手  机：13396038321
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包装：25kg,200kg
纯度：99%
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范德(北京)生物科技有限责任公司

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联系人：王
电  话：15911056312
手  机：15911056312
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包装：100mg
纯度：99.93%
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上海一基实业有限公司

特非那定
联系人：张嘉彬
电  话：021-60536261 17802116021
手  机：17802116021
Cas号：50679-08-8
包装：洽谈
纯度：
价格：洽谈
深圳市恒丰万达化工有限公司

特非那定
联系人：程超
电  话：0755-22677922-806
手  机：18126518403
Cas号：50679-08-8
包装：洽谈
纯度：
价格：洽谈
湖北鑫拓康楚源生物科技有限公司

特非那定
联系人：方彩静
电  话：027-52343735
手  机：13129951824
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包装：洽谈
纯度：
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扬州市朝宇物资有限公司

特非那定
联系人：礼
电  话：15152764754
手  机：
Cas号：50679-08-8
包装：洽谈
纯度：
价格：洽谈

Name:	Terfenadine Material Safety Data Sheet
Synonym:
CAS:	50679-08-8

CAS#	Chemical Name	content	EINECS#
50679-08-8	Terfenadine		256-710-8

特非那定

特非那定 制备方法及用途

制备方法

合成制备方法

用途简介

用途

特非那定 物化性质

特非那定 安全信息

特非那定 毒理性

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

特非那定 MSDS

特非那定 海关数据

中国海关编码：2933399090

特非那定 分子结构与计算化学数据

计算化学数据

特非那定 上游产品

特非那定 下游产品

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特非那定（不合格）

湖北鑫鸣泰化学有限公司

特非那定

湖北江民泰华化工有限公司

特非那定

范德(北京)生物科技有限责任公司

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上海一基实业有限公司

特非那定

深圳市恒丰万达化工有限公司

特非那定

湖北鑫拓康楚源生物科技有限公司

特非那定

扬州市朝宇物资有限公司

特非那定

特非那定制备方法及用途

特非那定物化性质

特非那定安全信息

特非那定毒理性

特非那定海关数据

特非那定分子结构与计算化学数据

特非那定上游产品

特非那定下游产品