- 中文名称：
-
- 中文别名：
- diethyl 2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
- 英文名称：
- 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-, 3,5-diethylester
- 英文别名：
- diethyl 2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3,5-dicarboxylate;
SK&diethyl 1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]3,5-pyridinedicarboxylate;
Ftorin;
4-(2-Trifluoromethylphenyl)-3,5-dicarbethoxy-2,6-dimethyl-1,4-dihydropyridine;
3,5-dicarbethoxy-1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)pyridine;
2,6-Dimethyl-3,5-dicarbomethoxy-4-(o-trifluoromethylphenyl)-1,4-dihydropyridine [French];
4-<2-(trifluoromethyl)phenyl>-3,5-dicarboethoxy-1,4-dihydrolutidine;
diethyl 1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-pyridine-3,5-dicarboxylate;
1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-3,5-pyridinedicarboxylic acid,diethyl ester;
Ftorin (pharmaceutical)
- CAS No.：
- 23191-75-5
- 分 子 式：
-
C20H22F3NO4
- 分 子 量：
- 397.43
- 精确分子量：
- 397.15000
- PSA：
- 64.63000
- InChI：
- The Key: ACZJZGLXRPZSLI-UHFFFAOYSA-N3
- 安全术语：
- Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of F− and NOx.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 1.215g/cm3
- 沸点：
- 455.5ºC at 760 mmHg
- 闪点：
- 229.3ºC
- 折射率：
- 1.496
- 蒸汽压：
- 1.75E-08mmHg at 25°C
安全信息
- 危险类别码：
- 37
- RTECS号：
- ZH5200000
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US7977800
- CHEMICAL NAME :
- 3,5-Pyridinedicarboxylic acid,
1,4-dihydro-2,6-dimethyl-4-(alpha,alpha,alpha-trifluo
ro-o- tolyl)-, diethyl ester
- CAS REGISTRY NUMBER :
- 23191-75-5
- BEILSTEIN REFERENCE NO. :
- 0500244
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C20-H22-F3-N-O4
- MOLECULAR WEIGHT :
- 397.43
- WISWESSER LINE NOTATION :
- T6M DHJ B1 CVO2 DR BXFFF& EVO2 F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1225 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 17,956,1974
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 17,956,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1480 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 17,956,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section
Vascular - regional or general arteriolar or venous dilation
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation
of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1-
1967- Volume(issue)/page/year: 16,817,1982
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 700 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Cardiac - change in rate
Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 17,956,1974
