6alpha-氟-11beta-羟基-16alpha-甲基-3,20-二氧代孕甾烷-1,4-二烯-21-酸丁酯
- 中文名称：
- 6alpha-氟-11beta-羟基-16alpha-甲基-3,20-二氧代孕甾烷-1,4-二烯-21-酸丁酯
- 中文别名：
-
- 英文名称：
- Pregna-1,4-dien-21-oicacid, 6-fluoro-11-hydroxy-16-methyl-3,20-dioxo-, butyl ester, (6a,11b,16a)-
- 英文别名：
- butyl 2-[(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetate;
SH K 203;
Fluocortin butyl [USAN:BAN];
Vaspit;
Varlane;
EINECS 255-543-8;
Fluocortin butyl (USAN);
FLUOCORTIN BUTYL;
fluocortin butylester
- CAS No.：
- 41767-29-7
- 分 子 式：
-
C26H35FO5
- 分 子 量：
- 446.5515032
- 精确分子量：
- 446.24700
- PSA：
- 80.67000
- InChI：
- The Key: XWTIDFOGTCVGQB-FHIVUSPVSA-N3
- 分子结构式：
-
- SDS：
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6alpha-氟-11beta-羟基-16alpha-甲基-3,20-二氧代孕甾烷-1,4-二烯-21-酸丁酯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU4155000
- CHEMICAL NAME :
- Pregna-1,4-dien-21-oic acid,
6-fluoro-11-hydroxy-16-methyl-3,20-dioxo-, butyl
ester, (6-alpha,11-beta,16-alpha)-
- CAS REGISTRY NUMBER :
- 41767-29-7
- LAST UPDATED :
- 199103
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C26-H35-F-O5
- MOLECULAR WEIGHT :
- 446.61
- WISWESSER LINE NOTATION :
- L E5 B666 CV OV AHTTT&J A1 E1 FVVO4 G1 LF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2217,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2217,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2217,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2217,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2217,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2217,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2217,1977
