硫胺盐酸磷酸酯
- 中文名称：
- 硫胺盐酸磷酸酯
- 中文别名：
- 硫胺盐酸磷酸酯;
thiamine hydrochloride phosphate
- 英文名称：
- Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-,chloride, hydrochloride (1:1:1)
- 英文别名：
- thiamine hydrochloride phosphate
- CAS No.：
- 16028-14-1
- 分 子 式：
-
C12H18N4O4PS.ClH.Cl
- 分 子 量：
- 453.32
- 精确分子量：
- 434.03500
- PSA：
- 191.72000
- 安全术语：
- Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx, SOx, POx, and Cl−.
- 分子结构式：
-
- SDS：
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硫胺盐酸磷酸酯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XJ7024550
- CHEMICAL NAME :
- Thiazolium,
3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5
-(2-(phosphonooxy)eth yl)-, chloride,
monohydrochloride, dihydrate
- CAS REGISTRY NUMBER :
- 16028-14-1
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C12-H18-N4-O4-P-S.Cl.Cl-H.2H2-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1015 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 24,712,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 487 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 24,712,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 711 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 24,712,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 476 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 24,712,1969
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 287 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 24,712,1969
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10556 mg/kg/28D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 24,712,1969
