7-[(1R,2R,3R,5S)-3,5-二羟基-2-[(1E,3S)-3-羟基-1-癸烯基]环戊基]-(5Z)-5-庚烯酸
- 中文名称：
- 7-[(1R,2R,3R,5S)-3,5-二羟基-2-[(1E,3S)-3-羟基-1-癸烯基]环戊基]-(5Z)-5-庚烯酸
- 中文别名：
- 20-ETHYL PROSTAGLANDIN F2ALPHA
- 英文名称：
- 5-Heptenoic acid,7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-1-decenyl]cyclopentyl]-,(5Z)- (9CI)
- 英文别名：
- 20-ETHYL PROSTAGLANDIN F2ALPHA;
9ALPHA,11ALPHA,15S-TRIHYDROXY-20A,20B-DIHOMOPROSTA-5Z,13E-DIEN-1-OIC ACID
- CAS No.：
- 36950-85-3
- 分 子 式：
-
C22H38O5
- 分 子 量：
- 382.60
- 精确分子量：
- 382.27200
- PSA：
- 97.99000
- InChI：
- The Key: XSDVSOQSNGGUFY-GWSKAPOCSA-N3
- 安全术语：
- Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
- 分子结构式：
-
- SDS：
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7-[(1R,2R,3R,5S)-3,5-二羟基-2-[(1E,3S)-3-羟基-1-癸烯基]环戊基]-(5Z)-5-庚烯酸 物化性质
- 密度：
- 1.123 g/cm3
- 沸点：
- 551.7ºC at 760 mmHg
- 闪点：
- 301.5ºC
- 折射率：
- 1.559
7-[(1R,2R,3R,5S)-3,5-二羟基-2-[(1E,3S)-3-羟基-1-癸烯基]环戊基]-(5Z)-5-庚烯酸 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ9653000
- CHEMICAL NAME :
- 5-Heptenoic acid,
7-(3,5-dihydroxy-2-(3-hydroxy-1-decenyl)cyclopentyl)-
, (1R-(1-alpha(Z),2-beta(1E,3S*),3-alpha,5-alpha))-
- CAS REGISTRY NUMBER :
- 36950-85-3
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C22-H38-O5
- MOLECULAR WEIGHT :
- 382.60
- WISWESSER LINE NOTATION :
- L5TJ AQ B6VQ C1U1YQ7 DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 4 mg/kg
- SEX/DURATION :
- female 4-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
V.1- 1972- Volume(issue)/page/year: 2,375,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 40 mg/kg
- SEX/DURATION :
- female 19-20 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
V.1- 1972- Volume(issue)/page/year: 2,375,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- female 4-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
V.1- 1972- Volume(issue)/page/year: 2,375,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2250 ug/kg
- SEX/DURATION :
- female 4-6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
V.1- 1869- Volume(issue)/page/year: 238,400,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 100 ug/kg
- SEX/DURATION :
- female 4-6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
V.1- 1869- Volume(issue)/page/year: 238,400,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 150 ug/kg
- SEX/DURATION :
- female 4-6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
- REFERENCE :
- NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
V.1- 1869- Volume(issue)/page/year: 238,400,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 2500 ug/kg
- SEX/DURATION :
- female 14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
V.1- 1972- Volume(issue)/page/year: 2,375,1972
