[(2R)-2-吡咯烷-1-基环己基]N-(3-戊氧基苯基)氨基甲酸酯
- 中文名称：
- [(2R)-2-吡咯烷-1-基环己基]N-(3-戊氧基苯基)氨基甲酸酯
- 中文别名：
-
- 英文名称：
- Carbamic acid,N-[3-(pentyloxy)phenyl]-, (1R,2R)-2-(1-pyrrolidinyl)cyclohexyl ester, rel-
- 英文别名：
- (2R)-2-(1-Pyrrolidinyl)cyclohexyl [3-(pentyloxy)phenyl]carbamate;
Carbamic acid,N-[3-(pentyloxy)phenyl]-, (1R,2R)-2-(1-pyrrolidinyl)cyclohexyl ester, rel-
- CAS No.：
- 104485-01-0
- 分 子 式：
-
C22H34N2O3
- 分 子 量：
- 0
- 精确分子量：
- 374.25700
- PSA：
- 54.29000
- InChI：
- The Key: HVYGHQWGUABUST-SFTDATJTSA-N3
- 分子结构式：
-
- SDS：
- 查看
[(2R)-2-吡咯烷-1-基环己基]N-(3-戊氧基苯基)氨基甲酸酯 物化性质
- 密度：
- 1.1g/cm3
- 沸点：
- 463.8ºC at 760mmHg
- 闪点：
- 234.3ºC
- 折射率：
- 1.551
- 蒸汽压：
- 8.82E-09mmHg at 25°C
[(2R)-2-吡咯烷-1-基环己基]N-(3-戊氧基苯基)氨基甲酸酯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FD0406500
- CHEMICAL NAME :
- Carbamic acid, (3-(pentyloxy)phenyl)-,
2-(1-pyrrolidinyl)cyclohexyl ester, trans-(+-)-
- CAS REGISTRY NUMBER :
- 104485-01-0
- LAST UPDATED :
- 199503
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C22-H34-N2-O3
- MOLECULAR WEIGHT :
- 374.58
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1030 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 283 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 790 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 122 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2950 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 58 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 105 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna
Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976
