6-氯-1,1-二氧代-3-(苯基甲基)-3,4-二氢-2H-苯并[e][1,2,4]噻二嗪-7-磺酰胺
- 中文名称：
- 6-氯-1,1-二氧代-3-(苯基甲基)-3,4-二氢-2H-苯并[e][1,2,4]噻二嗪-7-磺酰胺
- 中文别名：
- 6-氯-1,1-二氧代-3-(苯基甲基)-3,4-二氢-2H-苯并[e][1,2,4]噻二嗪-7-磺酰胺
- 英文名称：
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-(phenylmethyl)-, 1,1-dioxide
- 英文别名：
- Benzylhydrochlorothiazide;
3-benzyl-6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
- CAS No.：
- 1824-50-6
- 分 子 式：
-
C14H14ClN3O4S2
- 分 子 量：
- 355.86286
- 精确分子量：
- 387.01100
- PSA：
- 135.12000
- InChI：
- The Key: BWSSMIJUDVUASQ-UHFFFAOYSA-N3
- 分子结构式：
-
- SDS：
- 查看
6-氯-1,1-二氧代-3-(苯基甲基)-3,4-二氢-2H-苯并[e][1,2,4]噻二嗪-7-磺酰胺 物化性质
- 密度：
- 1.526g/cm3
- 熔点：
- 254-256ºC (dec.)
- 沸点：
- 632.9ºC at 760mmHg
- 闪点：
- 336.6ºC
- 折射率：
- 1.644
- 蒸汽压：
- 6.33E-16mmHg at 25°C
6-氯-1,1-二氧代-3-(苯基甲基)-3,4-二氢-2H-苯并[e][1,2,4]噻二嗪-7-磺酰胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DK9400000
- CHEMICAL NAME :
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide,
6-chloro-3,4-dihydro-3-(phenylmethyl)-, 1,1-dioxide
- CAS REGISTRY NUMBER :
- 1824-50-6
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C14-H14-Cl-N3-O4-S2
- MOLECULAR WEIGHT :
- 387.88
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 21,775,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 21,775,1979
