8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐
- 中文名称：
- 8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐
- 中文别名：
- 8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐
- 英文名称：
- 1H-Pyrazino[3,2,1-jk]carbazole,2,3,3a,4,5,6-hexahydro-8-methyl-, hydrochloride (1:1)
- 英文别名：
- 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino-[3,2,1-jk]carbazole hydrochloride;
2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloride;
1,10-Trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino-(1,2-a) indolhydrochloride;
2,3,3A,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1J,K)carbazole hydrochloride;
Pyrazidole;
Pirlindole hydrochloride;
Einecs 240-307-9;
1,10-Trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-A)indole hydrochloride;
1H-Pyrazino(3,2,1-jk)carbazole,2,3,3A,4,5,6-hexahydro-8-methyl-,monohydrochloride;
1,10-Trimethylene-8-methyltetrahydropyrazino(1,2-A)indole hydrochloride;
pyrazidole hydrochloride
- CAS No.：
- 16154-78-2
- 分 子 式：
-
C15H18N2.ClH
- 分 子 量：
- 262.81
- 精确分子量：
- 262.12400
- PSA：
- 16.96000
- InChI：
- The Key: LIFOOCLGAAEVIF-UHFFFAOYSA-N3
- 安全术语：
- A poison by intraperitoneal, intravenous, and subcutaneous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx and HCl.
- 分子结构式：
-
- SDS：
- 查看
8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐 物化性质
- 密度：
- 1.29g/cm3
- 沸点：
- 422.6ºC at 760mmHg
- 闪点：
- 209.4ºC
- 蒸汽压：
- 2.39E-07mmHg at 25°C
8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐 安全信息
8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ3930000
- CHEMICAL NAME :
- 1H-Pyrazino(3,2,1-jk)carbazole,
2,3,3a,4,5,6-hexahydro-8-methyl-, monohydrochloride
- CAS REGISTRY NUMBER :
- 16154-78-2
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C15-H18-N2.Cl-H
- MOLECULAR WEIGHT :
- 262.81
- WISWESSER LINE NOTATION :
- T C6566 1A P BN NM&&TTJ F1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2060 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479,
Russia) History Unknown Volume(issue)/page/year: (3),17,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479,
Russia) History Unknown Volume(issue)/page/year: (3),17,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation
of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1-
1967- Volume(issue)/page/year: 18,94,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 112 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 38,5,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 175 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation).
Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
UK) V.30- 1967- Volume(issue)/page/year: 37,192,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 67 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - tremor
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 38,5,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 122 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4258043
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 ug/m3/4H/30D-I
- TOXIC EFFECTS :
- Endocrine - other changes
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Biochemical - Metabolism (Intermediary) - lipids including transport
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479,
Russia) History Unknown Volume(issue)/page/year: (3),17,1993
8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐 海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
8-甲基-2,3,3A,4,5,6-六氢-1H-吡嗪并-[3,2,1-JK]咔唑盐酸盐 上游产品
