N-甲基-N-(1-氧代吡啶-1-鎓-3-基)偶氮甲胺
- 中文名称：
- N-甲基-N-(1-氧代吡啶-1-鎓-3-基)偶氮甲胺
- 中文别名：
-
- 英文名称：
- Pyridine,3-(3,3-dimethyl-1-triazen-1-yl)-, 1-oxide
- 英文别名：
- N-methyl-N-[(1-oxidopyridin-1-ium-3-yl)diazenyl]methanamine;
Pyndt
- CAS No.：
- 21600-42-0
- 分 子 式：
-
C7H10N4O
- 分 子 量：
- 166.21
- 精确分子量：
- 166.08500
- PSA：
- 53.42000
- 安全术语：
- Poison by intravenous and subcutaneous routes. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
N-甲基-N-(1-氧代吡啶-1-鎓-3-基)偶氮甲胺 物化性质
- 密度：
- 1.16g/cm3
- 沸点：
- 335ºC at 760mmHg
- 闪点：
- 156.4ºC
- 折射率：
- 1.566
- 蒸汽压：
- 0.000124mmHg at 25°C
N-甲基-N-(1-氧代吡啶-1-鎓-3-基)偶氮甲胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XY2300000
- CHEMICAL NAME :
- Triazene, 3,3-dimethyl-1-(m-pyridyl-N-oxide)-
- CAS REGISTRY NUMBER :
- 21600-42-0
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C7-H10-N4-O
- MOLECULAR WEIGHT :
- 166.21
- WISWESSER LINE NOTATION :
- T6NJ AO CNUNN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 490 mg/kg/38W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Brain and Coverings - tumors
Peripheral Nerve and Sensation - peripheral nerve tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 540 mg/kg/36W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Brain and Coverings - tumors
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Heritable translocation test
MUTATION DATA
- TYPE OF TEST :
- Host-mediated assay
- TEST SYSTEM :
- Rodent - mouse Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 400 umol/kg
- REFERENCE :
- AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser
Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70-
Volume(issue)/page/year: 3,99,1973
