1-(4-氯苄基)-1H-吲唑-3-羧酸
- 中文名称：
- 1-(4-氯苄基)-1H-吲唑-3-羧酸
- 中文别名：
- AF 1312-TS
- 英文名称：
- 1H-Indazole-3-carboxylicacid, 1-[(4-chlorophenyl)methyl]-
- 英文别名：
- 1-[(4-chlorophenyl)methyl]indazole-3-carboxylic acid;
1-p-Chlorobenzyl-1H-indazole-3-carboxylic acid;
AF 1312-TS
- CAS No.：
- 50264-86-3
- 分 子 式：
-
C15H11ClN2O2
- 分 子 量：
- 286.73
- 精确分子量：
- 286.05100
- PSA：
- 55.12000
- InChI：
- The Key: KVJTUQKSWFBPHG-UHFFFAOYSA-N3
- 安全术语：
- Poison by intraperitoneal route. Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl− and NOx.
- 分子结构式：
-
- SDS：
- 查看
1-(4-氯苄基)-1H-吲唑-3-羧酸 物化性质
- 密度：
- 1.37g/cm3
- 沸点：
- 515.7ºC at 760 mmHg
- 闪点：
- 265.7ºC
- 折射率：
- 1.666
- 存储条件/存储方法：
- 库房低温通风干燥
1-(4-氯苄基)-1H-吲唑-3-羧酸 安全信息
1-(4-氯苄基)-1H-吲唑-3-羧酸 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NK7885000
- CHEMICAL NAME :
- 1H-Indazole-3-carboxylic acid,
1-((4-chlorophenyl)methyl)-
- CAS REGISTRY NUMBER :
- 50264-86-3
- BEILSTEIN REFERENCE NO. :
- 0888596
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C15-H11-Cl-N2-O2
- MOLECULAR WEIGHT :
- 286.73
- WISWESSER LINE NOTATION :
- T56 BNNJ B1R DG& DVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1140 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 58 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 19 gm/kg
- SEX/DURATION :
- male 63 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating
females per # males exposed to fertile nonpregnant females)
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
before birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 500 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3 gm/kg
- SEX/DURATION :
- male 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
Reproductive - Paternal Effects - other effects on male
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- Sperm Morphology
MUTATION DATA
- TEST SYSTEM :
- Primate - monkey
- DOSE/DURATION :
- 14400 mg/kg/24W (Intermittent)
- REFERENCE :
- EXMPA6 Experimental and Molecular Pathology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1962- Volume(issue)/page/year:
23,357,1975
1-(4-氯苄基)-1H-吲唑-3-羧酸 海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
