(R)-N-Boc-3-甲酸哌啶,163438-09-3，生产厂家，价格-洛克化工网移动版

(R)-N-Boc-3-甲酸哌啶

中文名称：: (R)-N-Boc-3-甲酸哌啶

中文别名：: N-Boc-(R)-3-甲酸哌啶;
(R)-N-Boc-3-甲酸哌啶;
(R)-1-Boc-3-哌啶甲酸;
N-Boc-R-3-甲酸哌啶;
1-Boc-D-六氢烟碱酸

英文名称：: (R)-Boc-Nipecotic acid

英文别名：: (R)-Boc-Nipecotic Acid;
(R)-1-Boc-nipecotic Acid;
N-Boc-R-3-carboxylic acid piperidine;
1-Boc-D-nipecotic acid;
(R)-Boc-Nip-OH;
(R)-1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid;
(R)-N-BOC-piperidine-3-carboxylic acid;
(3R)-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylic acid

CAS No.：: 163438-09-3

分子式：: C₁₁H₁₉NO₄

分子量：: 229.27

精确分子量：: 229.13100

PSA：: 66.84000

MDL：: MFCD00673775

BRN：: 5539297

InChI：: InChI=1/C11H19NO4/c1-11(2,3)16-10(15)12-6-4-5-8(7-12)9(13)14/h8H,4-7H2,1-3H3,(H,13,14)/p-1/t8-/m1/s13

危险品标志：: Xi:

风险术语：: 36/37/38;

安全术语：: 26-36;

分子结构式：

SDS：: 查看

(R)-N-Boc-3-甲酸哌啶制备方法及用途

制备方法

医药中间体。

用途简介

(R)-N-Boc-3-甲酸哌啶物化性质

外观与性状：: 白色固体
密度：: 1.164 g/cm3
沸点：: 353.2ºC at 760 mmHg
闪点：: 167.4ºC
蒸汽压：: 6.15E-06mmHg at 25°C
存储条件/存储方法：: 常温，密闭，避光
稳定性相关：: 常温常压下稳定
避免强氧化剂
其它信息：: 1.       性状：白色粉末

2.       密度（g/mL,25℃）：未确定

3.       相对蒸汽密度（g/mL,空气=1）：未确定

4.       熔点（ºC）：未确定

5.       沸点（ºC,常压）：未确定

6.       沸点（ºC,0.11hPa）：未确定

7.       折射率：未确定

8.       闪点（ºC）：未确定

9.       比旋光度（º）：未确定

10.    自燃点或引燃温度（ºC）：未确定

11.    蒸气压（mmHg,25ºC）：未确定

12.    饱和蒸气压（kPa,60ºC）：未确定

13.    燃烧热（KJ/mol）：未确定

14.    临界温度（ºC）：未确定

15.    临界压力（KPa）：未确定

16.    油水（辛醇/水）分配系数的对数值：未确定

17.    爆炸上限（%,V/V）：未确定

18.    爆炸下限（%,V/V）：未确定

19.    溶解性：未确定

(R)-N-Boc-3-甲酸哌啶安全信息

海关代码：: 2933399090
WGK_Germany：: 3
德国有关水污染物质的分类清单
危险类别码：: R36/37/38
安全说明：: S26-S36
安全标志：: S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
危险标志：: Xi:Irritant;

(R)-N-Boc-3-甲酸哌啶 MSDS

Material Safety Data Sheet

Section 1. Identiﬁcation of the substance
  (R)-1-Boc-piperidine-3-carboxylic acid
    Product Name:
    Synonyms:

Section 2. Hazards identiﬁcation
    Harmful by inhalation, in contact with skin, and if swallowed.
    H315:        Causes skin irritation
    H319:        Causes serious eye irritation
    H335:        May cause respiratory irritation
    P261:        Avoid breathing dust/fume/gas/mist/vapours/spray
    Wear protective gloves/protective clothing/eye protection/face protection
    P280:
    P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
    and easy to do – continue rinsing
    P304+P340:        IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
    P405:        Store locked up

Section 3. Composition/information on ingredients.
    (R)-1-Boc-piperidine-3-carboxylic acid
    Ingredient name:
    CAS number:        163438-09-3

Section 4. First aid measures
    Immediately wash skin with copious amounts of water for at least 15 minutes while removing
    Skin contact:
    contaminated clothing and shoes. If irritation persists, seek medical attention.
    Eye contact:        Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
    ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
    attention.
    Inhalation:        Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
    Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.
    Ingestion:

Section 5. Fire ﬁghting measures
    In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
    powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
    should be worn.

Section 6. Accidental release measures
    Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
    standards.
    Respiratory precaution:        Wear approved mask/respirator
    Hand precaution:        Wear suitable gloves/gauntlets
    Skin protection:        Wear suitable protective clothing
    Eye protection:        Wear suitable eye protection
    Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
    for disposal. See section 12.
    Environmental precautions: Do not allow material to enter drains or water courses.

Section 7. Handling and storage
    Handling:        This product should be handled only by, or under the close supervision of, those properly qualiﬁed
    in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
    health and chemical hazard data given on this sheet.
    Storage:        Store in closed vessels.

Section 8. Exposure Controls / Personal protection
    Engineering Controls: Use only in a chemical fume hood.
    Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
    General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section 9. Physical and chemical properties
    Not speciﬁed
    Appearance:
    Boiling point:        No data
    Melting point:        No data
    Flash point:        No data
    Density:        No data
    Molecular formula:        C11H19NO4
    Molecular weight:        229.3

Section 10. Stability and reactivity
    Conditions to avoid: Heat, ﬂames and sparks.
    Materials to avoid: Oxidizing agents.
    Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section 11. Toxicological information
No data.

Section 12. Ecological information
No data.

Section 13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section 14. Transportation information
Non-harzardous for air and ground transportation.

Section 15. Regulatory information
    No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
    302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
    Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A

(R)-N-Boc-3-甲酸哌啶海关数据

中国海关编码：2933399090

概述：: 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素：: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
摘要/Summary：: 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(R)-N-Boc-3-甲酸哌啶分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值（XlogP）:1.1

2.氢键供体数量:1

3.氢键受体数量:4

4.可旋转化学键数量:3

5.互变异构体数量:无

6.拓扑分子极性表面积66.8

7.重原子数量:16

8.表面电荷:0

9.复杂度:282

10.同位素原子数量:0

11.确定原子立构中心数量:1

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

(R)-N-Boc-3-甲酸哌啶上游产品

二碳酸二叔丁酯 3-哌啶甲酸 1-BOC-1,2,5,6-四氢吡啶-3-羧酸 (R)-1-叔丁氧羰基-3-哌啶甲酸乙酯氢溴酸槟榔碱

(R)-N-Boc-3-甲酸哌啶下游产品

6-溴-3-(1-甲基-1H-吡唑-4-基)-5-(3R)-3-哌啶基吡唑并[1,5-A]嘧啶-7-胺 (S)-2-(N-BOC-哌啶-3-基)-1H-苯并咪唑 N-[2-[(R)-(3-氯苯基)[(3R)-1-[[[(2S)-2-(甲基氨基)-3-[(3R)-四氢-2H-吡喃-3-基]丙基]氨基]羰基]-3-哌啶基]甲氧基]乙基]氨基甲酸甲酯 2,2,2-三氟乙酸盐 3R-1-BOC-3-[甲氧基(甲基)氨基甲酰]哌啶 (R)-1-叔丁氧羰-哌啶-3-羧酸甲酯