7'-去氧代-7'-[(1R)-1-羟基乙基]-(7'R)-疣孢菌素 A
- 中文名称：
- 7'-去氧代-7'-[(1R)-1-羟基乙基]-(7'R)-疣孢菌素 A
- 中文别名：
- RORIDIN A
- 英文名称：
- Verrucarin A,7'-deoxo-7'-[(1R)-1-hydroxyethyl]-, (7'R)-
- 英文别名：
- RORIDIN A;
roridin A from myrothecium sp cryst;
roridana;
Roridin A,Roridin C;
roridinea;
Einecs 238-783-8;
roridin a from myrothecium sp.
- CAS No.：
- 14729-29-4
- 分 子 式：
-
C29H40O9
- 分 子 量：
- 532.6225
- 精确分子量：
- 532.26700
- PSA：
- 124.05000
- EINECS：
- 238-783-8
- InChI：
- The Key: NSFWWJIQIKBZMJ-UOPUXJSFSA-N3
- 危险品标志：
T+
- 风险术语：
- 28
- 安全术语：
- 28-36/37-45
- 分子结构式：
-
- SDS：
- 查看
7'-去氧代-7'-[(1R)-1-羟基乙基]-(7'R)-疣孢菌素 A 物化性质
- 外观与性状：
- 粉末
- 密度：
- 1.29g/cm3
- 沸点：
- 752.4ºC at 760 mmHg
- 闪点：
- 246ºC
- 折射率：
- 1.58
- 蒸汽压：
- 3.92E-26mmHg at 25°C
7'-去氧代-7'-[(1R)-1-羟基乙基]-(7'R)-疣孢菌素 A 安全信息
- 风险类别：
- 6.1(a)
- 危险类别码：
- R28
- 安全说明：
- 28-36/37-45
- 危险标志：
- T+: Very toxic;
7'-去氧代-7'-[(1R)-1-羟基乙基]-(7'R)-疣孢菌素 A 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VL0355000
- CHEMICAL NAME :
- Roridin A
- CAS REGISTRY NUMBER :
- 14729-29-4
- LAST UPDATED :
- 198708
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C29-H40-O9
- MOLECULAR WEIGHT :
- 532.69
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
4,S124,1984
** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - muscle contraction or spasticity
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52
Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year:
4,135,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BIBIAU Biotechnology and Bioengineering. (John Wiley & Sons, Inc., 605
Third Ave., New York, NY 10158) V.4- 1962- Volume(issue)/page/year:
10,445,1968
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2300 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - ulceration or bleeding from large intestine
Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985
7'-去氧代-7'-[(1R)-1-羟基乙基]-(7'R)-疣孢菌素 A 上游产品
7'-去氧代-7'-[(1R)-1-羟基乙基]-(7'R)-疣孢菌素 A 下游产品
