- 中文名称：
-
- 中文别名：
- 1-Azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol hydrochloride
- 英文名称：
- 1-Azabicyclo[2.2.2]octane-3-methanol,a,a-diphenyl-, hydrochloride (1:1)
- 英文别名：
- 1-Azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol hydrochloride;
1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol,hydrochloride
- CAS No.：
- 10447-38-8
- 分 子 式：
-
C20H23NO.ClH
- 分 子 量：
- 329.90
- 精确分子量：
- 329.15500
- PSA：
- 23.47000
- InChI：
- The Key: MVCBFPDJWSQMNY-UHFFFAOYSA-N3
- 安全术语：
- Poison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 沸点：
- 430.2ºC at 760 mmHg
- 闪点：
- 208ºC
- 蒸汽压：
- 3.65E-08mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VD4830000
- CHEMICAL NAME :
- 3-Quinuclidinemethanol, alpha,alpha-diphenyl-,
hydrochloride
- CAS REGISTRY NUMBER :
- 10447-38-8
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H23-N-O.Cl-H
- MOLECULAR WEIGHT :
- 329.90
- WISWESSER LINE NOTATION :
- T66 A B CNTJ AXQR&R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 440 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation).
Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
UK) V.30- 1967- Volume(issue)/page/year: 40,42,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 370 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation).
Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
UK) V.30- 1967- Volume(issue)/page/year: 40,42,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 62 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation).
Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
UK) V.30- 1967- Volume(issue)/page/year: 40,42,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 860 mg/kg
- TOXIC EFFECTS :
- Vascular - BP elevation not characterized in autonomic section
Lungs, Thorax, or Respiration - bronchiolar dilation
Immunological Including Allergic - increased immune response
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 43,148,1980
海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
