环丙孕酮
- 中文名称：
- 环丙孕酮
- 中文别名：
- 环丙孕酮;
环丙氯地孕酮杂质F
- 英文名称：
- 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione,6-chloro-1,2-dihydro-17-hydroxy-, (1b,2b)-
- 英文别名：
- cyproterone;
Cyproterone
- CAS No.：
- 2098-66-0
- 分 子 式：
-
C22H27ClO3
- 分 子 量：
- 374.91
- 精确分子量：
- 416.17500
- PSA：
- 60.44000
- InChI：
- InChI=1/C22H27ClO3/c1-11(24)22(26)7-5-14-12-9-18(23)17-10-19(25)13-8-16(13)21(17,3)15(12)4-6-20(14,22)2/h9-10,12-16,26H,4-8H2,1-3H3/t12?,13-,14?,15?,16?,20+,21+,22+/m1/s13
- 分子结构式：
-
- SDS：
- 查看
环丙孕酮 制备方法及用途
制备方法
用于治疗性欲异常、前列腺肥大、前列腺症等病。
用途简介
环丙孕酮 物化性质
- 密度：
- 1.29 g/cm3
- 熔点：
- 237.5-240ºC
- 沸点：
- 521ºC at 760 mmHg
- 闪点：
- 268.9ºC
- 折射率：
- 1.604
- 蒸汽压：
- 4.92E-13mmHg at 25°C
环丙孕酮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GZ2228000
- CHEMICAL NAME :
- 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione,
6-chloro-1-beta,2-beta-dihydro- 17-hydroxy-
- CAS REGISTRY NUMBER :
- 2098-66-0
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C22-H27-Cl-O3
- MOLECULAR WEIGHT :
- 374.94
- WISWESSER LINE NOTATION :
- L F5 C6 B663 PV LU NUTJ B1 F1 GV1 GQ MG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 840 mg/kg
- SEX/DURATION :
- male 21 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 26,65,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 560 mg/kg
- SEX/DURATION :
- male 7 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 49,237,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1680 mg/kg
- SEX/DURATION :
- male 21 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 49,237,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- female 16-19 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ACEDAB Acta Endocrinologica, Supplementum (Copenhagen). (Periodica,
Skolegade 12 E, DK-2500 Valby, Denmark) No.1- 1948-
Volume(issue)/page/year: 90,139,1964
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intracerebral
- DOSE :
- 4 ug/kg
- SEX/DURATION :
- male 21 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for
Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
Volume(issue)/page/year: 27,319,1968
*** REVIEWS ***
TOXICOLOGY REVIEW
RPHRA6 Recent Progress In Hormone Research. Proceedings of the Laurentian
Hormone Conference. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1947- Volume(issue)/page/year: 26,337,1970
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环丙孕酮
- 联系人：shuen lu
- 电 话：8668091917
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- Cas号：2098-66-0
- 包装：洽谈
- 纯度：
- 价格：洽谈
