阿扎吩; 2-(4-甲基-1-哌嗪基)-10-甲基-3,4-二氮吩嗪二盐酸盐
- 中文名称：
- 阿扎吩; 2-(4-甲基-1-哌嗪基)-10-甲基-3,4-二氮吩嗪二盐酸盐
- 中文别名：
- 阿扎吩;
2-(4-甲基-1-哌嗪基)-10-甲基-3,4-二氮吩嗪二盐酸盐
- 英文名称：
- 5H-Pyridazino[3,4-b][1,4]benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-, hydrochloride (1:2)
- 英文别名：
- 5-methyl-3-(4-methylpiperazin-1-yl)pyridazino[3,4-b][1,4]benzoxazine,dihydrochloride;
Azaphenonxazine 2HCl;
5-methyl-3-(4-methyl-piperazin-1-yl)-5H-benzo[b]pyridazino[4,3-e][1,4]oxazine,dihydrochloride;
5H-Pyridazino(3,4-b)(1,4)benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-,dihydrochloride;
5-Methyl-3-(4-methyl-1-piperazinyl)-5H-pyridazino(3,4-b)(1,4)benzoxazine dihydrochloride;
Azaphen hydrochloride;
Azafen;
2-(4-Methyl-1-piperazinyl)-10-methyl-3,4-diazaphenoxazindihydrochlorid [German];
pipofezine,dihydrochloride;
Pipofezin hydrochloride;
5-methyl-3-(4-methylpiperazin-1-yl)-5h-pyridazino[3,4-b][1,4]benzoxazine dihydrochloride;
Azaphen
- CAS No.：
- 24853-80-3
- 分 子 式：
-
C16H19N5O.2ClH
- 分 子 量：
- 370.28
- 精确分子量：
- 369.11200
- PSA：
- 44.73000
- InChI：
- The Key: JVONTAXIALFQJM-UHFFFAOYSA-N3
- 分子结构式：
-
- SDS：
- 查看
阿扎吩; 2-(4-甲基-1-哌嗪基)-10-甲基-3,4-二氮吩嗪二盐酸盐 物化性质
- 沸点：
- 536ºC at 760 mmHg
- 闪点：
- 278ºC
- 蒸汽压：
- 1.46E-11mmHg at 25°C
- 存储条件/存储方法：
- 通风低温干燥
阿扎吩; 2-(4-甲基-1-哌嗪基)-10-甲基-3,4-二氮吩嗪二盐酸盐 安全信息
阿扎吩; 2-(4-甲基-1-哌嗪基)-10-甲基-3,4-二氮吩嗪二盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR6080000
- CHEMICAL NAME :
- 5H-Pyridazino(3,4-b)(1,4)benzoxazine,
5-methyl-3-(4-methyl-1-piperazinyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 24853-80-3
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C16-H19-N5-O.2Cl-H
- MOLECULAR WEIGHT :
- 370.32
- WISWESSER LINE NOTATION :
- T C666 BO DNN INJ I1 F- AT6N DNTJ D1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year:
114,787,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 490 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year:
114,787,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year:
114,787,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Behavioral - wakefulness
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation
of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1-
1967- Volume(issue)/page/year: 4,118,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year:
114,787,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 63 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation).
Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
UK) V.30- 1967- Volume(issue)/page/year: 37,2,1974
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und
Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr.
18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year:
114,787,1975
阿扎吩; 2-(4-甲基-1-哌嗪基)-10-甲基-3,4-二氮吩嗪二盐酸盐 海关数据
中国海关编码：2934999090
- 概述：
- 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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- 电 话：021-57520831
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- Cas号：24853-80-3
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