4-羟基-6-氯喹唑啉,16064-14-5，生产厂家，价格-洛克化工网移动版

4-羟基-6-氯喹唑啉

中文名称：: 4-羟基-6-氯喹唑啉

中文别名：: 6-氯-4(3H)-喹唑啉酮;
4-羟基-6-氯喹唑啉;
6-氯-4-羟基喹唑啉

英文名称：: 4(3H)-Quinazolinone,6-chloro-

英文别名：: 6-Chloro-3H-quinazolin-4-one;
6-Chloro-4-Hydroxyquinazoline;
6-chloro-1H-quinazolin-4-one;
6-CHLORO-QUINAZOLIN-4-OL;
6-Chloroquinazolin-4-ol

CAS No.：: 16064-14-5

分子式：: C₈H₅ClN₂O

分子量：: 180.59

精确分子量：: 180.00900

PSA：: 46.01000

InChI：: InChI=1/C8H5ClN2O/c9-5-1-2-7-6(3-5)8(12)11-4-10-7/h1-4H,(H,10,11,12)3

风险术语：: Xi:Irritant;

分子结构式：

SDS：: 查看

4-羟基-6-氯喹唑啉物化性质

密度：: 1.5 g/cm3
沸点：: 356.1ºC at 760 mmHg
闪点：: 169.2ºC
折射率：: 1.688
蒸汽压：: 2.99E-05mmHg at 25°C

4-羟基-6-氯喹唑啉安全信息

海关代码：: 2933990090
危险标志：: Xi: Irritant;

4-羟基-6-氯喹唑啉毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA2457000

CHEMICAL NAME :: 4(3H)-Quinazolinone, 6-chloro-

CAS REGISTRY NUMBER :: 16064-14-5

LAST UPDATED :: 198509

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H5-Cl-N2-O

MOLECULAR WEIGHT :: 180.60

WISWESSER LINE NOTATION :: T66 BVM ENJ IG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 404 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,1204,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 340 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,1204,1962

4-羟基-6-氯喹唑啉 MSDS

Material Safety Data Sheet

Section 1. Identiﬁcation of the substance
Product Name: 6-Chloro-4-quinazolone
Synonyms: 6-Chloroquinazolin-4(3H)-one; 6-chloro-4-quinazolinone; 6-chloroquinazolin-4-ol

Section 2. Hazards identiﬁcation
Harmful by inhalation, in contact with skin, and if swallowed.

Section 3. Composition/information on ingredients.
Ingredient name: 6-Chloro-4-quinazolone
CAS number: 16064-14-5

Section 4. First aid measures
    Skin contact:        Immediately wash skin with copious amounts of water for at least 15 minutes while removing
    contaminated clothing and shoes. If irritation persists, seek medical attention.
    Eye contact:        Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
    ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
    attention.
    Inhalation:        Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
    Ingestion:        Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section 5. Fire ﬁghting measures
    In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
    powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
    should be worn.

Section 6. Accidental release measures
    Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
    standards.
    Respiratory precaution:        Wear approved mask/respirator
    Hand precaution:        Wear suitable gloves/gauntlets
    Skin protection:        Wear suitable protective clothing
    Eye protection:        Wear suitable eye protection
    Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
    for disposal. See section 12.
    Environmental precautions: Do not allow material to enter drains or water courses.

Section 7. Handling and storage
    Handling:        This product should be handled only by, or under the close supervision of, those properly qualiﬁed
    in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
    health and chemical hazard data given on this sheet.
    Store in closed vessels.
    Storage:

Section 8. Exposure Controls / Personal protection
    Engineering Controls: Use only in a chemical fume hood.
    Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
    General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section 9. Physical and chemical properties
    Appearance:        Not speciﬁed
    Boiling point:        No data
    No data
    Melting point:
    Flash point:        No data
    Density:        No data
    Molecular formula:        C8H5ClN2O
    Molecular weight:        180.6

Section 10. Stability and reactivity
    Conditions to avoid: Heat, ﬂames and sparks.
    Materials to avoid: Oxidizing agents.
    Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride.

Section 11. Toxicological information
No data.

Section 12. Ecological information
No data.

Section 13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section 14. Transportation information
Non-harzardous for air and ground transportation.

Section 15. Regulatory information
    No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
    302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
    Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A

4-羟基-6-氯喹唑啉海关数据

中国海关编码：2933990090

概述：: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素：: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
摘要/Summary：: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-羟基-6-氯喹唑啉分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:1

3.氢键受体数量:1

4.可旋转化学键数量:0

5.互变异构体数量:3

6.拓扑分子极性表面积:41.5

7.重原子数量:12

8.表面电荷:0

9.复杂度:229

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

4-羟基-6-氯喹唑啉上游产品

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4-羟基-6-氯喹唑啉下游产品

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