盐酸大观霉素
- 中文名称：
- 盐酸大观霉素
- 中文别名：
- 盐酸大观霉素;
奇放素菌素盐酸盐
- 英文名称：
- 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, hydrochloride(1:2), (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
- 英文别名：
- spectinomycin dihydrochloride;
SPECTINOMYCIN DIHYDROCHLORIDE;
Spectinomycin Dihydrochloride
- CAS No.：
- 21736-83-4
- 分 子 式：
-
C14H24N2O7.2ClH
- 分 子 量：
- 405.27100
- 精确分子量：
- 404.11200
- PSA：
- 129.51000
- EINECS：
- 244-554-3
- InChI：
- InChI=1/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H33
- 分子结构式：
-
- SDS：
- 查看
盐酸大观霉素 物化性质
- 外观与性状：
- 粉末
- 密度：
- 1.43g/cm3
- 熔点：
- 194ºC
- 沸点：
- 583.1ºC at 760 mmHg
- 闪点：
- 306.4ºC
- 折射率：
- 1.586
- 蒸汽压：
- 5.05E-16mmHg at 25°C
盐酸大观霉素 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ0333500
- CHEMICAL NAME :
- 4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one,
decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis
(methylamino)-, dihydrochloride,
(2R-(2-alpha,4a-beta,5a-beta,6-beta,7-beta,8-
beta,9-alpha,9a-alpha,10a-beta))-
- CAS REGISTRY NUMBER :
- 21736-83-4
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C14-H24-N2-O7.2Cl-H
- MOLECULAR WEIGHT :
- 405.32
- WISWESSER LINE NOTATION :
- T C666 BO DO GV IOTJ E1 HQ KM1 LQ MM1 NQ &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,382,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2020 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,382,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,382,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,382,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,382,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,382,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 8400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,382,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,382,1982
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X5600
No. of Facilities: 28 (estimated)
No. of Industries: 2
No. of Occupations: 3
No. of Employees: 525 (estimated)
No. of Female Employees: 397 (estimated)
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