- 中文名称：
-
- 中文别名：
-
- 英文名称：
- 3(2H)-Pyridazinone,2-[3-[[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amino]propyl]-, hydrochloride(1:1)
- 英文别名：
- 2-{3-[(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)amino]propyl}-3(2H) -pyridazinone hydrochloride (1:1);
Guvacolinhydrobromid;
methyl 1,2,5,6-tetrahydronicotinate hydrobromide;
GYKI-12 743;
1,2,5,6-Tetrahydronicotinic Acid Methyl Ester Hydrobromide;
norarecoline;
1,2,5,6-Tetrahydro-nicotinic Acid Hydrochloride;
1,2,5,6-Tetrahydro-pyridin-3-carbonsaeure-methylester,Hydrobromid;
1,2,5,6-tetrahydropyridine-3-carboxylic acid methyl ester hydrobromide;
Guvacoline Hydrobromide;
Guvacine Methyl Ester Hydrobromide
- CAS No.：
- 110714-10-8
- 分 子 式：
-
C16H19N3O3.ClH
- 分 子 量：
- 337.8013
- 精确分子量：
- 337.11900
- PSA：
- 65.38000
- InChI：
- The Key: WJDFSAOMSJHHCG-UHFFFAOYSA-N3
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 沸点：
- 464.9ºC at 760mmHg
- 闪点：
- 235ºC
- 蒸汽压：
- 8.02E-09mmHg at 25°C
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR6340000
- CHEMICAL NAME :
- 3(2H)-Pyridazinone,
2-(3-(((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)amino
)propyl)-, monohydrochloride
- CAS REGISTRY NUMBER :
- 110714-10-8
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C16-H19-N3-O3.Cl-H
- MOLECULAR WEIGHT :
- 337.84
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4826845
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 98 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
14,622,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4826845
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4826845
