15(S)-15-甲基前列腺素
- 中文名称：
- 15(S)-15-甲基前列腺素
- 中文别名：
- 15(S)-15-甲基前列腺素
- 英文名称：
- Prosta-5,13-dien-1-oicacid, 9,11,15-trihydroxy-15-methyl-, methyl ester, (5Z,9a,11a,13E,15S)-
- 英文别名：
- 15(S)-15-Methyl prostaglandin;
CARBOPROST METHYL;
15-methyl-prostaglandinf2-alphamethylester;
Carboprost methyl ester;
METHYL CARBOPROST;
methyl (Z)-7-(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-((3S)-3-hydroxy-3-methyl-1-octenyl)cyclopentyl]-5-heptenoate;
15(s)15-methyl-pgf2-alphamethylester;
15-methyl-pgf2-alphamethylester
- CAS No.：
- 35700-21-1
- 分 子 式：
-
C22H38O5
- 分 子 量：
- 382.53
- 精确分子量：
- 382.27200
- PSA：
- 86.99000
- InChI：
- The Key: QQCOAAFKJZXJFP-MTCLOZLLSA-N3
- 分子结构式：
-
- SDS：
- 查看
15(S)-15-甲基前列腺素 物化性质
- 密度：
- 1.096 g/cm3
- 沸点：
- 501.7ºC at 760 mmHg
- 闪点：
- 162.2ºC
- 折射率：
- 1.544
15(S)-15-甲基前列腺素 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ9654500
- CHEMICAL NAME :
- 5-Heptenoic acid,
7-(3,5-dihydroxy-2-(3-hydroxy-3(S)-methyl-1-octenyl)c
yclopentyl)-, methyl ester
- CAS REGISTRY NUMBER :
- 35700-21-1
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C22-H38-O5
- MOLECULAR WEIGHT :
- 382.60
- WISWESSER LINE NOTATION :
- L5TJ AQ B2U4VO1 C1U1XQ5&1 DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 60 ug/kg
- SEX/DURATION :
- female 16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
V.1- 1972- Volume(issue)/page/year: 16,143,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 10 ug/kg
- SEX/DURATION :
- female 10 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 27,51,1983
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 60 ug/kg
- SEX/DURATION :
- female 7 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 22,57,1980
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 50 ug/kg
- SEX/DURATION :
- female 37 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co.,
11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
Volume(issue)/page/year: 124,495,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 78 ug/kg
- SEX/DURATION :
- female 25 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- OBGNAS Obstetrics and Gynecology. (Elsevier Science Pub. Co., Inc., 52
Vanderbilt Ave., New York, NY 10017) V.1- 1953- Volume(issue)/page/year:
48,221,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 4400 ug/kg
- SEX/DURATION :
- male 84 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating
females per # males exposed to fertile nonpregnant females)
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S,
Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 29,109,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 16800 ug/kg
- SEX/DURATION :
- male 84 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S,
Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 29,109,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intratesticular
- DOSE :
- 4400 ug/kg
- SEX/DURATION :
- male 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S,
Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 29,103,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intratesticular
- DOSE :
- 16800 ug/kg
- SEX/DURATION :
- male 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S,
Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 29,103,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 4 ug/kg
- SEX/DURATION :
- female 4 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 186,67,1973
15(S)-15-甲基前列腺素 海关数据
中国海关编码：2918990090
- 概述：
- 2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
