2-氨基-6-甲基二吡啶[1,2-A:3,2-D]咪唑盐酸盐水合
- 中文名称：
- 2-氨基-6-甲基二吡啶[1,2-A:3,2-D]咪唑盐酸盐水合
- 中文别名：
- 2-氨基-6-甲基二吡啶[1,2-A:3’,2’-D]咪唑盐酸盐水合;
2-氨基-6-甲基二吡啶并(1,2-A:3',2'-D)咪唑盐酸盐
- 英文名称：
- Pyrido[3',2':4,5]imidazo[1,2-a]pyridin-2-amine,6-methyl-
- 英文别名：
- Glu-P-1;
6-Me-Glu-P-2;
2-amino-6-methyldipyridi<1,2-a:3',2'-d>imidazole
- CAS No.：
- 67730-11-4
- 分 子 式：
-
C11H10N4
- 分 子 量：
- 198.25
- 精确分子量：
- 252.07800
- PSA：
- 65.44000
- InChI：
- The Key: AYLURHVFAYRSHT-UHFFFAOYSA-N3
- 安全术语：
- Confirmed carcinogen with experimental carcinogenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
2-氨基-6-甲基二吡啶[1,2-A:3,2-D]咪唑盐酸盐水合 物化性质
- 密度：
- 1.41g/cm3
- 熔点：
- >300ºC
- 沸点：
- 363.7ºC at 760mmHg
- 闪点：
- 173.8ºC
- 存储条件/存储方法：
- 库房通风低温干燥
2-氨基-6-甲基二吡啶[1,2-A:3,2-D]咪唑盐酸盐水合 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JM5620000
- CAS REGISTRY NUMBER :
- 67730-11-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 23
- MOLECULAR FORMULA :
- C11-H10-N4
- MOLECULAR WEIGHT :
- 198.25
- WISWESSER LINE NOTATION :
- T B656 AN CN HNJ DZ J1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9100 mg/kg/68W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Gastrointestinal - tumors
Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15200 mg/kg/58W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Vascular - tumors
Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17512 mg/kg/57W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Vascular - tumors
Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17212 mg/kg/47W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Vascular - tumors
Liver - tumors
- TYPE OF TEST :
- Morphological transformation
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- BBRCA9 Biochemical and Biophysical Research Communications. (Academic
Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year: 96,611,1980
*** REVIEWS ***
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 40,223,1986
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 40,223,1986
IARC Cancer Review:Group 2B
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
2-氨基-6-甲基二吡啶[1,2-A:3,2-D]咪唑盐酸盐水合 下游产品
