盐酸丙哌维林; 1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐
- 中文名称：
- 盐酸丙哌维林; 1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐
- 中文别名：
- 盐酸丙哌维林;
罗匹外宁;
1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐
- 英文名称：
- Benzeneacetic acid, a-phenyl-a-propoxy-, 1-methyl-4-piperidinylester, hydrochloride (1:1)
- 英文别名：
- Propiverine Hydrochloride;
Propiverine hydrochloride
- CAS No.：
- 54556-98-8
- 分 子 式：
-
C23H29NO3.ClH
- 分 子 量：
- 403.95
- 精确分子量：
- 403.19100
- PSA：
- 38.77000
- InChI：
- InChI=1/C24H31NO2.ClH/c1-3-4-17-24(20-11-7-5-8-12-20,21-13-9-6-10-14-21)23(26)27-22-15-18-25(2)19-16-22;/h5-14,22H,3-4,15-19H2,1-2H3;1H3
- 风险术语：
- 37/38-41
- 分子结构式：
-
- SDS：
- 查看
盐酸丙哌维林; 1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐 物化性质
- 外观与性状：
- 白色晶体粉末
- 熔点：
- 213-216ºC
- 沸点：
- 494.7ºC at 760 mmHg
- 闪点：
- 253ºC
盐酸丙哌维林; 1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐 安全信息
盐酸丙哌维林; 1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AH3297000
- CHEMICAL NAME :
- Acetic acid, diphenylpropoxy-, 1-methyl-4-piperidyl
ester, hydrochloride
- CAS REGISTRY NUMBER :
- 54556-98-8
- LAST UPDATED :
- 199403
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C23-H29-N-O3.Cl-H
- MOLECULAR WEIGHT :
- 403.99
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GEXXA8 German (East) Patent Document. (U.S. Patent and Trademark Office,
Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #139212
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 29 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GEXXA8 German (East) Patent Document. (U.S. Patent and Trademark Office,
Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #139212
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 18200 mg/kg/1Y-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Liver - changes in liver weight
Endocrine - changes in pituitary weight
- REFERENCE :
- JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological
Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 15,107,1990
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 250 mg/kg
- SEX/DURATION :
- female 17-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - stillbirth
Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
per # born alive)
Reproductive - Effects on Newborn - other neonatal measures or effects
- REFERENCE :
- JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological
Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 14(Suppl
2),221,1989
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 50 mg/kg
- SEX/DURATION :
- female 17-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - behavioral
Reproductive - Effects on Newborn - physical
Reproductive - Effects on Newborn - delayed effects
- REFERENCE :
- JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological
Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 14(Suppl
2),221,1989
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 250 mg/kg
- SEX/DURATION :
- female 17-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
- REFERENCE :
- JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological
Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 14(Suppl
2),221,1989
盐酸丙哌维林; 1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐 海关数据
中国海关编码：2933399090
- 概述：
- 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
盐酸丙哌维林; 1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐 上游产品
盐酸丙哌维林; 1-甲基-4-哌啶基二苯基丙氧乙酸酯盐酸盐 下游产品
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