甲氧夫啉
- 中文名称：
- 甲氧夫啉
- 中文别名：
- 甲氧夫啉;
甲氧佛林 麦托福
- 英文名称：
- Isoquinoline,1-[2-(4-chlorophenyl)ethyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-
- 英文别名：
- 1-[2-(4-chlorophenyl)ethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline;
Metofoline;
Metofolinum [INN-Latin];
Mesofolin;
Versidyne;
Ro 4-1778/1;
Metopholine;
Methopholine;
Methopholine [USAN];
(R)-6,7-Dimethoxy-2-methyl-1-(4-chlor-phenethyl)-1,2,3,4-tetrahydro-isochinolin;
ARC I-K-1;
NIH 7672
- CAS No.：
- 2154-02-1
- 分 子 式：
-
C20H24ClNO2
- 分 子 量：
- 345.90
- 精确分子量：
- 345.15000
- PSA：
- 21.70000
- InChI：
- The Key: YBCPYHQFUMNOJG-GOSISDBHSA-N3
- 安全术语：
- Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.
- 分子结构式：
-
- SDS：
- 查看
甲氧夫啉 物化性质
- 密度：
- 1.131g/cm3
- 沸点：
- 449.3ºC at 760mmHg
- 闪点：
- 225.5ºC
- 折射率：
- 1.559
- 蒸汽压：
- 2.89E-08mmHg at 25°C
甲氧夫啉 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NW7350000
- CHEMICAL NAME :
- Isoquinoline,
1-(p-chlorophenethyl)-1,2,3,4-tetrahydro-6,7-dimethox
y-2-methyl-
- CAS REGISTRY NUMBER :
- 2154-02-1
- LAST UPDATED :
- 199203
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C20-H24-Cl-N-O2
- MOLECULAR WEIGHT :
- 345.90
- WISWESSER LINE NOTATION :
- T66 CNT&J B2R DG& C1 HO1 IO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc.,
1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year:
5,318,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc.,
1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year:
5,318,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
Switzerland) V.1- 1945- Volume(issue)/page/year: 18,446,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
Switzerland) V.1- 1945- Volume(issue)/page/year: 18,446,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc.,
1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year:
5,318,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
11,966,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
6,334,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 295 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc.,
1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year:
5,318,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
Switzerland) V.1- 1945- Volume(issue)/page/year: 18,446,1962
推荐供应商
湖北恩星生物科技有限公司
甲氧夫啉
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：2154-02-1
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
