阿立哌唑氮氧化物
- 中文名称：
- 阿立哌唑氮氧化物
- 中文别名：
- 阿立哌唑氮氧化物
- 英文名称：
- Morphinan-6-ol,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, 17-oxide, (5a,6a)-
- 英文别名：
- Codeine N-Oxide;
(3S,4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-3-oxido-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-ol
- CAS No.：
- 3688-65-1
- 分 子 式：
-
C18H21NO4
- 分 子 量：
- 315.36
- 精确分子量：
- 315.14700
- PSA：
- 68.12000
- EINECS：
- 222-988-4
- InChI：
- The Key: BDLSDHWCOJPHIE-YMVRPXFZSA-N3
- 分子结构式：
-
- SDS：
- 查看
阿立哌唑氮氧化物 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QD1260000
- CHEMICAL NAME :
- Morphinan-6-alpha-ol,
7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-,
17-oxide
- CAS REGISTRY NUMBER :
- 3688-65-1
- LAST UPDATED :
- 199112
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H21-N-O4
- MOLECULAR WEIGHT :
- 315.40
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15
Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-
Volume(issue)/page/year: 80,1501,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15
Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-
Volume(issue)/page/year: 80,1501,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15
Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-
Volume(issue)/page/year: 80,1501,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 767 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon
Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year:
54,688,1958
