溴地斯的明
- 中文名称：
- 溴地斯的明
- 中文别名：
- 溴地斯的明;
丁双吡斯的明;
吡斯的明;
Triazine catalyst;
N,N',N"-Dimethylaminopropylhexahydrotriazine;
3,3',3''-(1,3,5-triazinane-1,3,5-triyl)tris(N,N-dimethylpropan-1-amine);
1,3,5-Tris(dimethylaminopropyl)-1,3,5-hexahydrotriazine;
1,3,5-Tris-(dimethylaminopropyl)-sym-hexahydrotriazine;
1,3,5-Tris(3-dimethylaminopropyl)hexahydro-s-triazine;
4-(pentyloxy)benzoate;
4-n-Amyloxybenzoic acid;
disodium 5,5'-[(2-hydroxypropane-1,3-diyl)bis(oxy)]bis(4-oxo-4H-chromene-2-carboxylate);
- 英文名称：
- Pyridinium,3,3'-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, bromide (1:2)
- 英文别名：
- Pyridinium, 3,3'-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, bromide (1:2);
3-Hydroxy-1-methylpyridinium bromide, hexamethylenebis[methylcarbamate] (6CI,7CI);
Pyridinium, 3,3'-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, dibromide (9CI);
Pyridinium, 3-hydroxy-1-methyl-, bromide, hexamethylenebis[methylcarbamate] (2:1) (8CI);
BC 51;
Distigmine bromide;
Distigmine dibromide;
Hexamarium;
Hexamarium bromide;
N,N'-Hexamethylenebis(3-N-methylcarbamoxy-1-methylpyridine)dibromide;
Ubretid;
Ubritil
- CAS No.：
- 15876-67-2
- 分 子 式：
-
C22H32N4O4.2Br
- 分 子 量：
- 576.40
- 精确分子量：
- 574.07903
- PSA：
- 66.84000
- EINECS：
- 240-013-0
- InChI：
- InChI=1/C22H32N4O4.2BrH/c1-23-13-9-11-19(17-23)29-21(27)25(3)15-7-5-6-8-16-26(4)22(28)30-20-12-10-14-24(2)18-20;;/h9-14,17-18H,5-8,15-16H2,1-4H3;2*1H/q+2;;/p-23
- 安全术语：
- Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx and Br−.
- 分子结构式：
-
- SDS：
- 查看
溴地斯的明 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UU5277000
- CHEMICAL NAME :
- Pyridinium, 3-hydroxy-1-methyl-, bromide,
hexamethylenebis(methylcarbamate)
- CAS REGISTRY NUMBER :
- 15876-67-2
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C22-H32-N4-O4.2Br
- MOLECULAR WEIGHT :
- 576.40
- WISWESSER LINE NOTATION :
- T6KJ A1 COVN1&6N1&VO- DT6KJ A1 &E 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 900 ug/kg/3D
- TOXIC EFFECTS :
- Autonomic Nervous System - parasympatholytic
Vascular - other changes
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- JJTOEX Japanese Journal of Toxicology. (Yakugyo Jihosha, Hokushin Bldg.,
2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo, 101, Japan) V.1- 1988-
Volume(issue)/page/year: 4,383,1991
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 700 ug/kg/7D-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - visual field changes
Sense Organs and Special Senses (Eye) - diplopia
Behavioral - hallucinations, distorted perceptions
- REFERENCE :
- BJCPAT British Journal of Clinical Practice. (Medical News Group, 1 Bedford
St., London WC2E 9HD, UK) V.10(10)- 1956- Volume(issue)/page/year:
48,103,1994
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,68,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 740 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,349,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1080 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,349,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 740 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,68,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,68,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 310 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,349,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,349,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,68,1969
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溴地斯的明
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