美法仑
- 中文名称：
- 美法仑
- 中文别名：
-
- 英文名称：
- Phenylalanine,4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)
- 英文别名：
- Phenylalanine,4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1);
Dl-alanine,3-(p-[bis(2-chloroethyl)amino]phenyl)-,hydrochloride;
MELPHALAN raceMic Mixture;
4-[bis-(2-chloro-ethyl)-amino]-DL-phenylalanine,hydrochloride;
Dl-phenylalanine,4-[bis(2-chloroethyl)amino]-,monohydrochloride;
sarcolysine;
4-[bis(2-chloroethyl)amino]-DL-phenylalanine monohydrochloride;
Alanine,3-[p-[bis(2-chloroethyl)amino]phenyl]-,hydrochloride,DL;
Dl-phenylalanine mustard hydrochloride;
Alanine,3-[p-[bis(2-chloroethyl)amino]phenyl]-,monohydrochloride,DL;
4-[Bis-(2-chlor-aethyl)-amino]-DL-phenylalanin,Hydrochlorid
- CAS No.：
- 1465-26-5
- 分 子 式：
-
C13H18Cl2N2O2.ClH
- 分 子 量：
- 341.69
- 精确分子量：
- 340.05100
- PSA：
- 66.56000
- InChI：
- The Key: OUUYBRCCFUEMLH-UHFFFAOYSA-N3
- 安全术语：
- Poison by ingestion. intraperitoneal, and intravenous route. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
- 分子结构式：
-
- SDS：
- 查看
美法仑 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY3980000
- CHEMICAL NAME :
- Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-,
hydrochloride, DL
- CAS REGISTRY NUMBER :
- 1465-26-5
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 20
- MOLECULAR FORMULA :
- C13-H18-Cl2-N2-O2.Cl-H
- MOLECULAR WEIGHT :
- 341.69
- WISWESSER LINE NOTATION :
- QVYZ1R DN2G2G &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 52 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea
Endocrine - changes in spleen weight
Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 16200 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise
specified
Gastrointestinal - hypermotility, diarrhea
Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intratracheal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis)
Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 44600 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise
specified
Gastrointestinal - hypermotility, diarrhea
Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 430 ug/kg
- TOXIC EFFECTS :
- Blood - leukopenia
Blood - thrombocytopenia
Blood - other changes
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 860 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
Blood - leukopenia
Blood - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 41600 ug/kg/13W-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Blood - changes in leukocyte (WBC) count
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 mg/m3/2H/30D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition
Blood - changes in spleen
Blood - changes in leukocyte (WBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 66 mg/kg/1Y-I
- TOXIC EFFECTS :
- Blood - changes in spleen
Related to Chronic Data - death
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 1200 umol/L
- REFERENCE :
- BEXBAN Bulletin of Experimental Biology and Medicine (English Translation).
Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY
10013) V.41- 1956- Volume(issue)/page/year: 92,943,1981
美法仑 海关数据
中国海关编码：2923900090
- 概述：
- 2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
推荐供应商
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美法仑
- 联系人：刘经理
- 电 话：020-38082199
- 手 机：18928798886
- Cas号：1465-26-5
- 包装：洽谈
- 纯度：
- 价格：洽谈
