苯喹胺
- 中文名称：
- 苯喹胺
- 中文别名：
-
- 英文名称：
- 2H-Benzo[a]quinolizine-3-carboxamide,2-(acetyloxy)-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-,(2R,3R,11bS)-rel-
- 英文别名：
- Emete-con;
Quantryl;
Quantril
- CAS No.：
- 23844-24-8
- 分 子 式：
-
C22H32N2O5
- 分 子 量：
- 404.56
- 精确分子量：
- 404.23100
- PSA：
- 68.31000
- InChI：
- The Key: JSZILQVIPPROJI-GBESFXJTSA-N3
- 安全术语：
- Poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
苯喹胺 物化性质
- 密度：
- 1.19g/cm3
- 熔点：
- 130-131.5ºC
- 沸点：
- 531ºC at 760mmHg
- 闪点：
- 274.9ºC
- 存储条件/存储方法：
- 通风低温干燥
苯喹胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DK1575000
- CHEMICAL NAME :
- 2H-Benzo(a)quinolizine-3-carboxamide,
N,N-diethyl-1,3,4,6,7,11b-hexahydro-2-hydroxy-
9,10-dimethoxy-, acetate (ester)
- CAS REGISTRY NUMBER :
- 23844-24-8
- LAST UPDATED :
- 199510
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C22-H32-N2-O5
- MOLECULAR WEIGHT :
- 404.56
- WISWESSER LINE NOTATION :
- T B666 GNTT&J DOV1 EVN2&2 LO1 MO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1050 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,208,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,208,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 580 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,208,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 321 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DIPHAH Dissertationes Pharmaceuticae. (Warsaw, Poland) V.1-17, 1949-65.
For publisher information, see PJPPAA. Volume(issue)/page/year: 17,145,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,208,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
21,315,1972
