甲磺酸硫达唑嗪; N,N-二甲基-10-[3-(4-甲基哌嗪-1-基)丙基]吩噻嗪-2-磺酰胺甲磺酸盐
- 中文名称：
- 甲磺酸硫达唑嗪; N,N-二甲基-10-[3-(4-甲基哌嗪-1-基)丙基]吩噻嗪-2-磺酰胺甲磺酸盐
- 中文别名：
- 甲磺酸硫达唑嗪;
N,N-二甲基-10-[3-(4-甲基哌嗪-1-基)丙基]吩噻嗪-2-磺酰胺甲磺酸盐
- 英文名称：
- Thioproperazine dimesylate
- 英文别名：
- N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide,methanesulfonic acid;
10-[3-(4-methyl-piperazin-1-yl)-propyl]-10H-phenothiazine-2-sulfonic acid dimethylamide,bis-methanesulfonate;
Mageptyl;
thioproperazine dimethanosulphonate;
Thioproperazine dimesylate;
Thioperazine methanesulfate;
thioproperazine mesylate;
Thioproperazindimethansulfat;
Majeptil;
Thioproperazine dimesilate;
Thioperazine dimethanesulfonate;
Thioproperazine mesilate;
Thioproperazine dimethanesulfonate;
thioproperazine dimethansulfonate
- CAS No.：
- 2347-80-0
- 分 子 式：
-
C22H30N4O2S2.2(CH4O3S)
- 分 子 量：
- 638.84
- 精确分子量：
- 638.15700
- PSA：
- 206.28000
- EINECS：
- 219-074-2
- InChI：
- InChI=1/C22H30N4O2S2.2CH4O3S/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25;2*1-5(2,3)4/h4-5,7-10,17H,6,11-16H2,1-3H3;2*1H3,(H,2,3,4)3
- 分子结构式：
-
- SDS：
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甲磺酸硫达唑嗪; N,N-二甲基-10-[3-(4-甲基哌嗪-1-基)丙基]吩噻嗪-2-磺酰胺甲磺酸盐 物化性质
- 熔点：
- 218-222ºC
- 沸点：
- 612.2ºC at 760mmHg
- 闪点：
- 324°C
- 蒸汽压：
- 6.32E-15mmHg at 25°C
甲磺酸硫达唑嗪; N,N-二甲基-10-[3-(4-甲基哌嗪-1-基)丙基]吩噻嗪-2-磺酰胺甲磺酸盐 安全信息
甲磺酸硫达唑嗪; N,N-二甲基-10-[3-(4-甲基哌嗪-1-基)丙基]吩噻嗪-2-磺酰胺甲磺酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SP5425000
- CHEMICAL NAME :
- Phenothiazine-2-sulfonamide,
N,N-dimethyl-10-(3-(4-methyl-1-piperazinyl)propyl)-,
dimethanesulfonate
- CAS REGISTRY NUMBER :
- 2347-80-0
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C22-H30-N4-O2-S2.2C-H4-O3-S
- MOLECULAR WEIGHT :
- 638.90
- WISWESSER LINE NOTATION :
- T C666 BN ISJ ESWN1&1 B3- AT6N DNTJ D1 &OSW1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 59 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 5 mg/kg
- REFERENCE :
- CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK.
(Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974-
Volume(issue)/page/year: 9(5),14,1975
