普拉维林盐酸盐
- 中文名称：
- 普拉维林盐酸盐
- 中文别名：
-
- 英文名称：
- Cyclohexanamine,N-(1-methylethyl)-4,4-diphenyl-, hydrochloride (1:1)
- 英文别名：
- 4,4-diphenyl-N-propan-2-ylcyclohexan-1-amine,hydrochloride;
4,4-Diphenylcyclohexyl(isopropyl)ammonium chloride;
Pramiverin hydrochloride;
EMD 9806;
HSP 2986;
Sistalgin;
4,4-Diphenyl-N-isopropylcyclohexylamine hydrochloride;
Monoverin;
EINECS 238-284-5;
Pramiverine hydrochloride
- CAS No.：
- 14334-41-9
- 分 子 式：
-
C21H27N.ClH
- 分 子 量：
- 329.95
- 精确分子量：
- 329.19100
- PSA：
- 12.03000
- 安全术语：
- Poison by ingestion and intravenous routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and HCl.
- 分子结构式：
-
- SDS：
- 查看
普拉维林盐酸盐 物化性质
- 沸点：
- 406.9ºC at 760 mmHg
- 闪点：
- 206ºC
- 蒸汽压：
- 7.83E-07mmHg at 25°C
普拉维林盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GX1210000
- CHEMICAL NAME :
- Cyclohexylamine, 4,4-diphenyl-N-isopropyl-,
hydrochloride
- CAS REGISTRY NUMBER :
- 14334-41-9
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C21-H27-N.Cl-H
- MOLECULAR WEIGHT :
- 329.95
- WISWESSER LINE NOTATION :
- L6TJ AR& AR& DMY1&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 623 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,703,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,703,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 346 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,703,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,703,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,703,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,703,1976
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 500 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,703,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 650 mg/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 26,703,1976
