三甲曲沙葡糖醛酸酯
- 中文名称：
- 三甲曲沙葡糖醛酸酯
- 中文别名：
- 葡醛酸三甲曲沙;
三甲曲沙葡糖醛酸酯;
5-甲基-6-[[(3,4,5-三甲氧基苯基)氨基]甲基]喹唑啉-2,4-二胺 D-葡糖醛酸盐
- 英文名称：
- trimetrexate glucuronate
- 英文别名：
- CI 898 trihydrochloride,5-Methyl-6-[[(3,4,5-trimethoxyphenyl)amino]methyl]-2,4-quinazolinediaminetrihydrochloride;
CI 898 dihydrochloride;
CI 898 TRIHYDROCHLORIDE;
Trimetrexate glucuronate
- CAS No.：
- 82952-64-5
- 分 子 式：
-
C19H23N5O3.C6H10O7
- 分 子 量：
- 563.56
- 精确分子量：
- 563.22300
- PSA：
- 244.99000
- 分子结构式：
-
- SDS：
- 查看
三甲曲沙葡糖醛酸酯 物化性质
- 密度：
- 1.305 g/cm3
- 沸点：
- 647ºC at 760 mmHg
- 闪点：
- 345.1ºC
三甲曲沙葡糖醛酸酯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LZ8945000
- CAS REGISTRY NUMBER :
- 82952-64-5
- LAST UPDATED :
- 199412
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C19-H23-N5-O3.C6-H10-O7
- MOLECULAR WEIGHT :
- 563.63
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 2027 ug/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section
Gastrointestinal - other changes
Blood - thrombocytopenia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 4054 mg/kg/3W-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg/5D-C
- TOXIC EFFECTS :
- Blood - changes in leukocyte (WBC) count
Blood - changes in platelet count
Related to Chronic Data - changes in testicular weight
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 500 nmol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
40,1981,1990
推荐供应商
湖北恩星生物科技有限公司
葡醛酸三甲曲沙
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：82952-64-5
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
