哌草丹,61432-55-1，生产厂家，价格-洛克化工网移动版

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基本信息

制备方法及用途

物化性质

安全信息

毒理性

结构与计算化学

表征图谱

哌草丹

中文名称：: 哌草丹

中文别名：: 哌草丹;
哌啶酯;
优克稗;
S-1-甲基-苯基乙基哌啶-1-硫代甲酸酯;
S-(1-甲基-1-苯乙基)-1-哌啶硫代甲酸酯;
S-(Α,Α-二甲基苄基)哌啶-1-硫代甲酸酯;
S-1-甲基-1-苯基乙基哌啶-1-硫代甲酸酯

英文名称：: 1-Piperidinecarbothioicacid, S-(1-methyl-1-phenylethyl) ester

英文别名：: Dimepiperate;
s-(2-phenyl-2-propanyl)-1-piperidincarbothioat;
S-1-methyl-1-phenylethyl piperidine-1-carbothioate;
S-(2-phenylpropan-2-yl) piperidine-1-carbothioate;
S-1-Methyl-1-phenylethyl piperidine 1-carbothioate;
EINECS 262-784-2;
S-(1-methyl-1-phenylethyl) 1-piperidinecarbothioate;
Yukamate

CAS No.：: 61432-55-1

分子式：: C₁₅H₂₁NOS

分子量：: 263.4

精确分子量：: 263.13400

PSA：: 45.61000

MDL：: MFCD00274592

EINECS：: 262-784-2

危险品标志：: Xn，N

风险术语：: R22;R51/53;

安全术语：: S61

分子结构式：

SDS：: 查看

哌草丹制备方法及用途

制备方法

以甲苯或哌啶为溶剂，加入α，α-二甲基苄硫醇，然后在室温下滴加40%氢氧化钠溶液，回流反应，分去水分。升温至60～70℃，滴加哌啶甲酰氯，滤去析出的氯化钠，升温反应数小时，经水洗、干燥、脱溶得哌草丹。α，α-二甲基苄硫醇的合成方法如下：以1，4-二氧六环为溶剂，在催化剂存在下，α-甲基苯乙烯与硫化氢反应制得，收率86.3%。也可采用二甲基亚砜为溶剂，将相应的硝基化合物用Na2S2处理，所得物在0℃与铝汞齐作用制得，收率达92%。

合成制备方法

以甲苯或哌啶为溶剂，加入α，α-二甲基苄硫醇，然后在室温下滴加40%氢氧化钠溶液，回流反应，分去水分。升温至60～70℃，滴加哌啶甲酰氯，滤去析出的氯化钠，升温反应数小时，经水洗、干燥、脱溶得哌草丹。
α，α-二甲基苄硫醇的合成方法如下：以1，4-二氧六环为溶剂，在催化剂存在下，α-甲基苯乙烯与硫化氢反应制得，收率86.3%。
也可采用二甲基亚砜为溶剂，将相应的硝基化合物用Na2S2处理，所得物在0℃与铝汞齐作用制得，收率达92%。

用途简介

内吸传导型选择性稻田除草剂。对防除2叶期以前的稗草效果突出。药剂由根系、茎、叶吸收后传导至整个植株，打破内源生长素的平衡，进而使细胞内蛋白质合成受阻，破坏生长点细胞的分裂，达到抑制和延迟杂草茎叶的形成，生长发育停止，茎叶由浓绿变黄、变褐至枯死。如水稻旱种田在出苗后，稗草 5～ 5叶期，每百平方米用哌草丹50%乳油30mL加20%敌稗乳油75～ 6mL，对水 5～6kg，茎叶喷雾。旱育秧及湿润秧苗在播前或播后，每百平方米用50%乳油 5～30mL，对水 75～ 5kg床面喷雾，水育秧苗可在播后1～4d用毒土法施药。插秧田在插秧后3～7d，用50%乳油 5～39mL对水喷雾。施药后保持3～5cm水层5～7d。当稻田杂草种类较多时，宜与其他除草剂混用。

用途

内吸传导型选择性稻田除草剂。对防除2叶期以前的稗草效果突出。药剂由根系、茎、叶吸收后传导至整个植株，打破内源生长素的平衡，进而使细胞内蛋白质合成受阻，破坏生长点细胞的分裂，达到抑制和延迟杂草茎叶的形成，生长发育停止，茎叶由浓绿变黄、变褐至枯死。如水稻旱种田在出苗后，稗草1.5～2.5叶期，每百平方米用哌草丹50%乳油30mL加20%敌稗乳油75～112.6mL，对水4.5～6kg，茎叶喷雾。旱育秧及湿润秧苗在播前或播后，每百平方米用50%乳油22.5～30mL，对水3.75～4.5kg床面喷雾，水育秧苗可在播后1～4d用毒土法施药。插秧田在插秧后3～7d，用50%乳油22.5～39mL对水喷雾。施药后保持3～5cm水层5～7d。当稻田杂草种类较多时，宜与其他除草剂混用。

哌草丹毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM5958000

CHEMICAL NAME :: 1-Piperidinecarbothioic acid, S-(1-methyl-1-phenylethyl) ester

CAS REGISTRY NUMBER :: 61432-55-1

LAST UPDATED :: 199512

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C15-H21-N-O-S

MOLECULAR WEIGHT :: 263.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 946 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (45),18,1984

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1600 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (45),18,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 676 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (45),18,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 18836 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (45),18,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4519 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (45),18,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1211 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (45),18,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (45),18,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1092 mg/kg/13W-C

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 13140 mg/kg/2Y-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 54600 mg/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 263 gm/kg/2Y-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thyroid weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 14,109,1989

毒理学数据：: 雄性大鼠急性经口LD₅₀ 946mg /kg ,雌性为959mg /kg，雄小鼠为4677mg /kg ,雌小鼠为4519mg /kg。大鼠(雄、雌)急性经皮LD₅₀ > 5000mg /kg。大鼠腹膜注射LD₅₀ 676-798mg /kg，小鼠皮下注射LD₅₀ > 10000mg /kg。鲤鱼LC₅₀5.8 mg/L (48h}，虹鳟鱼5.7m/L }48h)，水蚤40mg/L ( 3h )。雄性日本鹤鹑急性经口LD₅₀> 2000mg /kg，母鸡LD₅₀> SOOOmg /kg

生态数据：: 若无政府许可，勿将材料排入周围环境

上海吉至生化科技有限公司

哌草丹

联系人：Shirley张
电话：021-57520831
手机：18116052675

Cas号：61432-55-1
包装：100mgea
纯度：98%(分析标准试剂）
价格：488.0元

苏州市森菲达化工有限公司

哌草丹

联系人：吴
电话：15195660023
手机：15195660023

Cas号：61432-55-1
包装：200kg
纯度：
价格：洽谈

武汉鹏垒生物科技有限公司

哌草丹

联系人：何
电话：15871464247
手机：15871464247

Cas号：61432-55-1
包装：1kg
纯度：
价格：洽谈

寿光市乐吉农化有限公司

哌草丹

联系人：柳庆祝
电话：0536-5106123
手机：

Cas号：61432-55-1
包装：洽谈
纯度：
价格：洽谈

哌草丹

哌草丹制备方法及用途

制备方法

合成制备方法

用途简介

用途

哌草丹物化性质

哌草丹安全信息

哌草丹毒理性

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

哌草丹分子结构与计算化学数据

计算化学数据

哌草丹表征图谱

推荐供应商

上海吉至生化科技有限公司

哌草丹

苏州市森菲达化工有限公司

哌草丹

武汉鹏垒生物科技有限公司

哌草丹

寿光市乐吉农化有限公司

哌草丹

哌草丹

哌草丹 制备方法及用途

制备方法

合成制备方法

用途简介

用途

哌草丹 物化性质

哌草丹 安全信息

哌草丹 毒理性

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

哌草丹 分子结构与计算化学数据

计算化学数据

哌草丹 表征图谱

推荐供应商

上海吉至生化科技有限公司

哌草丹

苏州市森菲达化工有限公司

哌草丹

武汉鹏垒生物科技有限公司

哌草丹

寿光市乐吉农化有限公司

哌草丹

哌草丹制备方法及用途

哌草丹物化性质

哌草丹安全信息

哌草丹毒理性

哌草丹分子结构与计算化学数据

哌草丹表征图谱