盐酸依米丁
- 中文名称：
- 盐酸依米丁
- 中文别名：
- 二盐酸吐根碱;
盐酸吐根碱;
吐根碱盐酸盐
- 英文名称：
- EMETINE DIHYDROCHLORIDE
- 英文别名：
- EMETINE DIHYDROCHLORIDE;
Emetin-Dihydrochlorid;
Emetin-hydrochlorid;
emetine hydrochloride;
amebicide;
emetine chloride;
EMETINE 2HCL;
purum;
EMETINE DIHCL;
(-)-emetine,dihydrochloride;
Emetine HCL USP
- CAS No.：
- 316-42-7
- 分 子 式：
- C29H42Cl2N2O4
- 分 子 量：
- 553.56
- 精确分子量：
- 552.25200
- PSA：
- 52.19000
- MDL：
- MFCD00149309
- EINECS：
- 206-259-8
- BRN：
- 5216794
- InChI：
- The Key: HUEYSSLYFJVUIS-MRFSYGAJSA-N3
- 风险术语：
- 28-36/37/38
- SDS：
- 查看
盐酸依米丁 物化性质
- 外观与性状：
- 白色粉末或晶体
- 熔点：
- 240-250ºC (dec., dry matter)(lit.)
- 沸点：
- 600.3ºC at 760 mmHg
- 闪点：
- 316.9ºC
- 存储条件/存储方法：
2-8℃储存。
- 其它信息：
一、物性数据
性状：不可用
密度（g/mL,25/4℃）： 不可用
相对蒸汽密度（g/mL,空气=1）：不可用
熔点（ºC）：240-250
沸点（ºC,常压）：不可用
沸点（ºC,5.2kPa）： 不可用
折射率： 不可用
闪点（ºC）： 不可用
比旋光度（º）： 不可用
自燃点或引燃温度（ºC）： 不可用
蒸气压（kPa,25ºC）： 不可用
饱和蒸气压（kPa,60ºC）： 不可用
燃烧热（KJ/mol）：不可用
临界温度（ºC）： 不可用
临界压力（KPa）： 不可用
油水（辛醇/水）分配系数的对数值：不可用
爆炸上限（%,V/V）：不可用
爆炸下限（%,V/V）： 不可用
溶解性：不可用
盐酸依米丁 安全信息
- 风险类别：
- 6.1(a)
- 危险类别码：
- 28-36/37/38
- 安全标志：
- S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S28:接触皮肤之后，立即使用大量皂液洗涤。
S45:出现意外或者感到不适，立刻到医生那里寻求帮助（最好带去产品容器标签）。
: - 危险标志：
- T+: Very toxic;
盐酸依米丁 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JY5250000
- CHEMICAL NAME :
- Emetine, dihydrochloride
- CAS REGISTRY NUMBER :
- 316-42-7
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 23
- MOLECULAR FORMULA :
- C29-H40-N2-O4.2Cl-H
- MOLECULAR WEIGHT :
- 553.63
- WISWESSER LINE NOTATION :
- T B666 GNTT&J E2 LO1 MO1 D1- BT66 CMT&J HO1 IO1 &GH &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Human
- REFERENCE :
- BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 4,111,1947 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 2770 ug/kg/4D-I
- TOXIC EFFECTS :
- Behavioral - hallucinations, distorted perceptions Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- AIMDAP Archives of Internal Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1908- Volume(issue)/page/year: 17,420,1916
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 25 mg/kg/20D-I
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- AIMDAP Archives of Internal Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1908- Volume(issue)/page/year: 17,420,1916
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 8,297,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 17 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,431,1948
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,474,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 8,297,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 62 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,431,1948
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 37 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16,65,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 16200 ug/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 39,43,1950
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
- REFERENCE :
- AIMDAP Archives of Internal Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1908- Volume(issue)/page/year: 17,420,1916
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIMDAP Archives of Internal Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1908- Volume(issue)/page/year: 17,420,1916
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 13886 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IMGAAY Indian Medical Gazette. (Block F, 105-C, New Alipore, Calcutta 700 053, India) V.1-90, 1866-1955; New series: V.1- 1961- Volume(issue)/page/year: 49,85,1914
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Cardiac - other changes Lungs, Thorax, or Respiration - chronic pulmonary edema Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- AJTMAQ American Journal of Tropical Medicine. (Baltimore, MD) V.1-31, 1921-51. For publisher information, see AJTHAB. Volume(issue)/page/year: 10,249,1930
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIMDAP Archives of Internal Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1908- Volume(issue)/page/year: 17,420,1916
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Cardiac - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- AJTMAQ American Journal of Tropical Medicine. (Baltimore, MD) V.1-31, 1921-51. For publisher information, see AJTHAB. Volume(issue)/page/year: 10,249,1930
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 13886 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IMGAAY Indian Medical Gazette. (Block F, 105-C, New Alipore, Calcutta 700 053, India) V.1-90, 1866-1955; New series: V.1- 1961- Volume(issue)/page/year: 49,85,1914
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2500 ug/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage)
- REFERENCE :
- JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 62,501,1914
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1355,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 56200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20700 ug/kg/6D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 39,43,1950
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 35 mg/kg/7W-I
- TOXIC EFFECTS :
- Cardiac - EKG changes not diagnostic of specified effects Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JCPCDT Journal of Cardiovascular Pharmacology. (Raven Press, 1140 Ave. of the Americas, New York, NY 10036) V.1- 1979- Volume(issue)/page/year: 2,155,1980
- 毒理学数据：
二、毒理学数据：
急性毒性：不可用 。
- 生态数据：
三、生态学数据：
1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。
盐酸依米丁 MSDS
Section I.Chemical Product and Company Identification
Chemical Name Emetine Hydrochloride
Portland OR
Synonym Amebicide
Chemical Formula C29H40N2O4•2HCl•xH2O
CAS Number 316-42-7
Section II. Composition and Information on Ingredients
Chemical Name CAS Number Percent (%) TLV/PEL Toxicology Data
Emetine Hydrochloride 316-42-7 Min. 98.0 (T) Not available. Rat LD50 (intraperitoneal) 17mg/kg
Rat LD50 (oral) 120mg/kg
Rat LD50 (subcutaneous) 95mg/kg
Section III. Hazards Identification
Acute Health Effects Highly toxic if ingested or inhaled. Avoid prolonged contact with this material. Overexposure may result in serious illness
or death. Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system.
Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching,
scaling, reddening, or, occasionally, blistering. Follow safe industrial hygiene practices and always wear proper
protective equipment when handling this compound.
CARCINOGENIC EFFECTS : Not available.
Chronic Health Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Section IV. First Aid Measures
Eye Contact Check for and remove any contact lenses. IMMEDIATELY flush eyes with runing water for at least 15 minutes. keeping
eyelids open. COLD water may be used. DO NOT use an eye oitment. Flush eyes with running water for a minimum of
15 minutes, occasionally lifting the upper eyelids. Seek medical attention. Treat symptomatically and supportively.
Skin Contact After contact with skin, wash immediately with plenty of water. Gently and thorough wash the contaminated skin with
running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. COLD water
may be used. Cover the irritated skin with an emollient. Seek medical attention. Treat symptomatically and supportively.
Wash any contaminated clothing before reusing.
Inhalation Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If
breathing is difficult, administer oxygen. If the victim is not breathing, perform artificial respiration. WARNING: It may be
dangerous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious
or corrosive. Seek immediate medical attention and, if possible, show the chemical label. Treat symptomatically and
supportively.
Ingestion INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.
Loosen tight clothing such as a collar, tie, belt, or waistband. If the victim is not breathing, administer artificial respiration.
Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material
was ingested; the absence of such signs, however, is not conclusive. Seek immediate medical attention and, if possible,
show the chemical label. Treat symptomatically and supportively.
Section V. Fire and Explosion Data
Not available.
Flammability May be combustible at high temperature. Auto-Ignition
Flammable Limits
Flash Points Not available.
Not available.
Combustion Products These products are toxic carbon oxides (CO, CO 2), nitrogen oxides (NO, NO2), halogenated compounds.
WARNING: Highly toxic HCl gas is produced during combustion.
Fire Hazards
No specific information is available regarding the flammability of this compound in the presence of various materials.
Continued on Next Page
Emetine Hydrochloride
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards
Risks of explosion of the product in presence of static discharge: Not available.
No additional information is available regarding the risks of explosion.
Fire Fighting Media
SMALL FIRE: Use DRY chemicals, CO 2, water spray or foam.
and Instructions LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
Section VI. Accidental Release Measures
Spill Cleanup
Highly toxic material. Irritating material.
In case of a spill and/or a leak, always shut off any sources of ignition, ventilate the area, and exercise caution. Use a
Instructions
shovel to put the material into a convenient waste disposal container. Consult federal, state, and/or local authorities for
assistance on disposal.
Section VII. Handling and Storage
Handling and Storage HIGHLY TOXIC. IRRITANT. Handle with caution and minimize exposure. Keep away from heat and sources of ignition.
Mechanical exhaust required. When not in use, tightly seal the container and store in a dry, cool place. Avoid excessive
Information
heat and light. DO NOT ingest. DO NOT breathe dust. Wear suitable protective clothing. If ingested, seek medical
advice immediately and show the container or the label. Treat symptomatically and supportively.
Always store away from incompatible compounds such as oxidizing agents.
Section VIII. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Splash goggles. Lab coat. Dust respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling
this product.
Exposure Limits Not available.
Section IX. Physical and Chemical Properties
Solubility
Physical state @ 20°C White to pale-yellow powder. 1g dissolves in about 7mL water.
Soluble in alcohol.
Not available.
Specific Gravity
Molecular Weight 553.56 (Anh) Partition Coefficient Not available.
Boiling Point Not available. Vapor Pressure Not available.
Melting Point 235°C (decomp.) Vapor Density Not available.
Not available. Volatility Not available.
Refractive Index
Critical Temperature Odor Not available.
Not available.
Not available. Not available.
Viscosity Taste
Section X. Stability and Reactivity Data
Stability
This material is stable if stored under proper conditions. (See Section VII for instructions)
Conditions of Instability
Avoid excessive heat and light.
Incompatibilities
Reactive with strong oxidizing agents.
Section XI. Toxicological Information
RTECS Number JY5250000
Routes of Exposure Eye contact. Ingestion. Inhalation. Skin contact.
Rat LD50 (intraperitoneal) 17mg/kg
Toxicity Data
Rat LD50 (oral) 120mg/kg
Rat LD50 (subcutaneous) 95mg/kg
CARCINOGENIC EFFECTS : Not available.
Chronic Toxic Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Continued on Next Page
Emetine Hydrochloride
Acute Toxic Effects Highly toxic if ingested or inhaled. Avoid prolonged contact with this material. Overexposure may result in serious illness
or death. Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system.
Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching,
scaling, reddening, or, occasionally, blistering. Follow safe industrial hygiene practices and always wear proper
protective equipment when handling this compound.
Section XII. Ecological Information
Ecotoxicity Not available.
Not available.
Environmental Fate
Section XIII. Disposal Considerations
Recycle to process, if possible. Consult your local or regional authorities. You may be able to dissolve or mix material with
Waste Disposal
a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state, and local regulations when disposing of the substance.
Section XIV. Transport Information
DOT Classification DOT CLASS 6.1: Toxic material.
PIN Number
Proper Shipping Name
Alkaloids solid, n.o.s.
Packing Group (PG) II
DOT Pictograms
Section XV. Other Regulatory Information and Pictograms
TSCA Chemical Inventory This compound is ON the EPA Toxic Substances Control Act (TSCA) inventory list.
(EPA)
WHMIS Classification
Not available.
(Canada)
EINECS Number (EEC) 206-259-8
EEC Risk Statements R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38- Irritating to eyes, respiratory system and skin.
Japanese Regulatory Data
SECTION 16 - ADDITIONAL INFORMATION
N/A
盐酸依米丁 分子结构与计算化学数据
计算化学数据
1.疏水参数计算参考值（XlogP）:无
2.氢键供体数量:3
3.氢键受体数量:6
4.可旋转化学键数量:7
5.互变异构体数量:无
6.拓扑分子极性表面积52.2
7.重原子数量:37
8.表面电荷:0
9.复杂度:679
10.同位素原子数量:0
11.确定原子立构中心数量:4
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:3
