SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifiers
Product name : Lithium diisopropylamide mono(tetrahydrofuran)
solution
REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Flammable liquids (Category 2), H225
Acute toxicity, Inhalation (Category 4), H332
Skin corrosion (Category 1B), H314
Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336
Aspiration hazard (Category 1), H304
Acute aquatic toxicity (Category 1), H400
Chronic aquatic toxicity (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
F Highly flammable R11
C Corrosive R34
Xn Harmful R65, R20
N Dangerous for the R50/53
environment
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Danger
Hazard statement(s)
H225 Highly flammable liquid and vapour.
H304 May be fatal if swallowed and enters airways.
H314 Causes severe skin burns and eye damage.
H332 Harmful if inhaled.
H336 May cause drowsiness or dizziness.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P261 Avoid breathing vapours.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/
physician.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard none
Statements
According to European Directive 67/548/EEC as amended.
Hazard symbol(s) F Highly flammable
C Corrosive
N Dangerous for the environment
R-phrase(s)
R11 Highly flammable.
R20 Harmful by inhalation.
R34 Causes burns.
R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
R65 Harmful: may cause lung damage if swallowed.
S-phrase(s)
S16 Keep away from sources of ignition - No smoking.
S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S45 In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
S62 If swallowed, do not induce vomiting: seek medical advice immediately
and show this container or label.
Other hazards - none
SECTION 3: Composition/information on ingredients
Mixtures
Formula : C10H22LiNO
Molecular Weight : 179,23 g/mol
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Cyclohexane
CAS-No. 110-82-7 Flam. Liq. 2; Acute Tox. 4; 50 - 100 %
EC-No. 203-806-2 Skin Irrit. 2; STOT SE 3; Asp.
Index-No. 601-017-00-1 Tox. 1; Aquatic Acute 1;
Aquatic Chronic 1; H225,
H304, H315, H332, H336,
H410
N-(1-Methylethyl)-2-propanamine lithium salt, compd. with Tetrahydrofuran (1:1)
CAS-No. 123333-84-6 Skin Corr. 1B; H314 25 - 50 %
Ethylbenzene
CAS-No. 100-41-4 Flam. Liq. 2; Acute Tox. 4; 10 - 20 %
EC-No. 202-849-4 H225, H332
Index-No. 601-023-00-4
Hazardous ingredients according to Directive 1999/45/EC
Component Classification Concentration
Cyclohexane
CAS-No. 110-82-7 F, Xn, N, R11 - R20 - R38 - 50 - 100 %
EC-No. 203-806-2 R65 - R67 - R50/53
Index-No. 601-017-00-1
N-(1-Methylethyl)-2-propanamine lithium salt, compd. with Tetrahydrofuran (1:1)
CAS-No. 123333-84-6 C, R34 25 - 50 %
Ethylbenzene
CAS-No. 100-41-4 F, Xn, R11 - R20 10 - 20 %
EC-No. 202-849-4
Index-No. 601-023-00-4
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16
SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Consult a
physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
no data available
SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx), Lithium oxides
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation.
Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to
form explosive concentrations. Vapours can accumulate in low areas.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
place in container for disposal according to local regulations (see section 13).
Reference to other sections
For disposal see section 13.
SECTION 7: Handling and storage
Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
charge.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature: 2 - 8 °C
Handle and store under inert gas. Air and moisture sensitive.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection
tested and approved under appropriate government standards such as NIOSH (US) or EN
166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, Flame retardant antistatic protective clothing, The type
of protective equipment must be selected according to the concentration and amount of the
dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
the environment must be avoided.
SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing no data available
point
f) Initial boiling point and no data available
boiling range
g) Flash point -18 °C - closed cup
h) Evapouration rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density 0,816 g/cm3
n) Water solubility no data available
o) Partition coefficient: n- no data available
octanol/water
p) Auto-ignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
no data available
Conditions to avoid
Heat, flames and sparks. Extremes of temperature and direct sunlight.
Incompatible materials
Strong bases, Oxidizing agents, Strong oxidizing agents, Copper, Strong acids, Plastics
Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5
SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitisation
no data available
Germ cell mutagenicity
Carcinogenicity
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Ethylbenzene)
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Styrene)
Reproductive toxicity
Lithium and its compounds are possible teratogens by analogy to lithium carbonate which has equivocal
human teratogenic data and positive animal teratogenic data.
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Additional Information
RTECS: Not available
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and
skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi,
pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath,
Headache, Nausea
Endocrine system. - (Styrene)
Liver - Irregularities - Based on Human Evidence (Diisopropylamine)
SECTION 12: Ecological information
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
Very toxic to aquatic life with long lasting effects.
SECTION 13: Disposal considerations
Waste treatment methods
Product
Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting
as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal
company.
Contaminated packaging
Dispose of as unused product.
SECTION 14: Transport information
UN number
ADR/RID: 2924 IMDG: 2924 IATA: 2924
UN proper shipping name
ADR/RID: FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Ethylbenzene, Cyclohexane, N-(1-Methylethyl)-
2-propanamine lithium salt, compd. with Tetrahydrofuran (1:1))
IMDG: FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Ethylbenzene, Cyclohexane, N-(1-Methylethyl)-
2-propanamine lithium salt, compd. with Tetrahydrofuran (1:1))
IATA: Flammable liquid, corrosive, n.o.s. (Ethylbenzene, Cyclohexane, N-(1-Methylethyl)-2-
propanamine lithium salt, compd. with Tetrahydrofuran (1:1))
Transport hazard class(es)
ADR/RID: 3 (8) IMDG: 3 (8) IATA: 3 (8)
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available
SECTION 15: Regulatory information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
Acute Tox. Acute toxicity
Aquatic Acute Acute aquatic toxicity
Aquatic Chronic Chronic aquatic toxicity
Asp. Tox. Aspiration hazard
Flam. Liq. Flammable liquids
H225 Highly flammable liquid and vapour.
H304 May be fatal if swallowed and enters airways.
H314 Causes severe skin burns and eye damage.
H315 Causes skin irritation.
H332 Harmful if inhaled.
H336 May cause drowsiness or dizziness.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.
Skin Corr. Skin corrosion
Skin Irrit. Skin irritation
STOT SE Specific target organ toxicity - single exposure
Full text of R-phrases referred to under sections 2 and 3
C Corrosive
F Highly flammable
N Dangerous for the environment
R11 Highly flammable.
R20 Harmful by inhalation.
R34 Causes burns.
R38 Irritating to skin.
R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.
R65 Harmful: may cause lung damage if swallowed.
R67 Vapours may cause drowsiness and dizziness.
Xn Harmful
Further information
Copyright 2014 Co. LLC. License granted to make unlimited paper copies for internal use
only.
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our knowledge
and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Corporation and its Affiliates shall not be held
liable for any damage resulting from handling or from contact with the above product. See
and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
