替苯丙胺
- 中文名称：
- 替苯丙胺
- 中文别名：
- 替苯丙胺
- 英文名称：
- 1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE
- 英文别名：
- (±)-MDA [(±)-3,4-Methylenedioxyamphetamine];
3,4-methylenedioxyamphetamine;
3,4-methylenedioxyphenylisopropylamine;
rac-3,4-methylenedioxyamphetamine;
Tenamphetamine;
8-hydroxymethyl-1,2,3,5,6,7,8,9-octahydroindolizine
- CAS No.：
- 4764-17-4
- 分 子 式：
-
C10H13NO2
- 分 子 量：
- 179.22
- 精确分子量：
- 179.09500
- PSA：
- 44.48000
- InChI：
- The Key: NGBBVGZWCFBOGO-UHFFFAOYSA-N3
- SDS：
- 查看
替苯丙胺 物化性质
- 密度：
- 1.163 g/cm3
- 沸点：
- 281.7ºC at 760mmHg
- 闪点：
- 134.9ºC
- 折射率：
- 1.564
替苯丙胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SI0580000
- CHEMICAL NAME :
- Phenethylamine, alpha-methyl-3,4-(methylenedioxy)-
- CAS REGISTRY NUMBER :
- 4764-17-4
- BEILSTEIN REFERENCE NO. :
- 0150196
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H13-N-O2
- MOLECULAR WEIGHT :
- 179.24
- WISWESSER LINE NOTATION :
- T56 BO DO CHJ G1YZ1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 13300 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - convulsions or effect on seizure threshold
Skin and Appendages - hair
- REFERENCE :
- CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher
information, see JTCTDW. Volume(issue)/page/year: 6,193,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 58300 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - excitement
Skin and Appendages - hair
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 214,133,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 31100 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - convulsions or effect on seizure threshold
Skin and Appendages - hair
- REFERENCE :
- TRBMAV Texas Reports on Biology and Medicine. (Galveston, TX) V.1-41(2),
1943-81/82. Discontinued. Volume(issue)/page/year: 33,610,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,798,1986
*** REVIEWS ***
TOXICOLOGY REVIEW
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher
information, see JTCTDW. Volume(issue)/page/year: 6,45,1973