安钠咖
- 中文名称：
- 安钠咖
- 中文别名：
- 安钠咖
- 英文名称：
- CAFFEINE-SODIUM BENZOATE
- 英文别名：
- sodium,1,3,7-trimethylpurine-2,6-dione,benzoate;
Caffeine sodium benzoate;
1,3,7-Trimethyl-3,7-dihydro-purin-2,6-dion;
Sodium benzoate and caffeine;
Kaffein,Verbindung mit Natriumbenzoat;
Sodium caffeine benzoate;
CAFFEINE and SODIUM BENZOATE;
Caffeine sodium benzoicum;
Caffeine benzoate sodium;
1,3,7-trimethyl-3,7-dihydro-purine-2,6-dione,caffeine,compound with sodium benzoate;
Annaca
- CAS No.：
- 8000-95-1
- 分 子 式：
-
C15H15N4NaO4
- 分 子 量：
- 338.29
- 精确分子量：
- 338.09900
- PSA：
- 101.95000
- InChI：
- The Key: JWBPVFVNISJVEM-UHFFFAOYSA-M3
- 风险术语：
- 22
- SDS：
- 查看
安钠咖 安全信息
- 包装等级：
- III
- 风险类别：
- 6.1(b)
- 危险类别码：
- 22
- 危险标志：
- Xn: Harmful;
安钠咖 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EV6640000
- CHEMICAL NAME :
- Caffeine and sodium benzoate
- CAS REGISTRY NUMBER :
- 8000-95-1
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C8-H10-N4-O2.C7-H5-O2.Na
- MOLECULAR WEIGHT :
- 338.33
- WISWESSER LINE NOTATION :
- T56 BN DN FNVNVJ B1 F1 H1 &OVR &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 860 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,31,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,31,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 525 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 116,343,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New
York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year:
21,1,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 83,1,1945
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - mating performance (e.g. # sperm positive females
per # females mated; # copulations per # estrus cycles)
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H
St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year:
127,84,1958
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X3987
No. of Facilities: 14 (estimated)
No. of Industries: 1
No. of Occupations: 3
No. of Employees: 487 (estimated)
No. of Female Employees: 380 (estimated)