盐酸普萘洛尔
- 中文名称：
- 盐酸普萘洛尔
- 中文别名：
- 盐酸普萘洛尔;
盐酸心得安;
普萘洛尔,心得安
- 英文名称：
- Propranolol hydrochloride,(RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanolhydrochloride
- 英文别名：
- Propranolol hydrochloride,(RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanolhydrochloride;
PENTAPROPANOLOLHYDROCHLORIDE;
PROPANOLOL HYDROCHLORIDE;
dl-propranolol hcl;
L-Propranololhydrochlorid;
DL-PROPRANOLOL HYDROCHLORIDE;
dl-propranololhydrochloridebp;
PROPRANOLOL HCL;
dl-propranololHClbp
- CAS No.：
- 3506-09-0
- 分 子 式：
-
C16H22ClNO2
- 分 子 量：
- 295.80400
- 精确分子量：
- 295.13400
- PSA：
- 41.49000
- EINECS：
- 206-268-7
- InChI：
- The Key: ZMRUPTIKESYGQW-PFEQFJNWSA-N3
- 风险术语：
- 22
- SDS：
- 查看
盐酸普萘洛尔 制备方法及用途
制备方法
用于各种功能性心律失常、室上性及室性异位期外收缩、心房纤维颤动和麻醉引起的心律不齐等。
用途简介
盐酸普萘洛尔 物化性质
- 外观与性状：
- 白色粉末
- 熔点：
- 163-165 °C(lit.)
- 沸点：
- 446.1ºC at 760 mmHg
- 闪点：
- 223.6ºC
盐酸普萘洛尔 安全信息
- 包装等级：
- III
- 风险类别：
- 6.1(b)
- 海关代码：
- 2933990090
- WGK_Germany：
- 3
德国有关水污染物质的分类清单
- 危险类别码：
- 22
- RTECS号：
- UB7525000
- 危险标志：
- Xn
盐酸普萘洛尔 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UB7526000
- CHEMICAL NAME :
- 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-,
hydrochloride, (+-)-
- CAS REGISTRY NUMBER :
- 3506-09-0
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C16-H21-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 295.84
- WISWESSER LINE NOTATION :
- L66J BO1YQ1MY1&1 &GH (+-)
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 449 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479,
Russia) History Unknown Volume(issue)/page/year: (2),41,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 231 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479,
Russia) History Unknown Volume(issue)/page/year: (2),41,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 87600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 24,1751,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 33300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 24,1751,1974
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 440 mg/kg
- SEX/DURATION :
- female 11-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
- REFERENCE :
- NEUIDS Neurochemistry International. (Pergamon Press Inc., Headington Hill
Hall, Oxford OX3 0BW, United Kingdom) V.1- 1980-
Volume(issue)/page/year: 22,589,1993
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 210 mg/kg
- SEX/DURATION :
- female 8-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - behavioral
- REFERENCE :
- EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB
211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year:
195,75,1991
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 130 mg/kg
- SEX/DURATION :
- female 7-19 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - other effects to embryo
Reproductive - Specific Developmental Abnormalities - respiratory system
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 252,42,1990
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X6883
No. of Facilities: 10 (estimated)
No. of Industries: 1
No. of Occupations: 2
No. of Employees: 7622 (estimated)
No. of Female Employees: 7177 (estimated)
盐酸普萘洛尔 海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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湖北恩星生物科技有限公司
盐酸普萘洛尔
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：3506-09-0
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
武汉金诺化工有限公司
盐酸普萘洛尔
- 联系人：周源
- 电 话：+86-027-87661180
- 手 机：15071086981
- Cas号：3506-09-0
- 包装：洽谈
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- 价格：洽谈