(1-氨基-甲基苯)磷酸,18108-22-0，生产厂家，价格-洛克化工网移动版

(1-氨基-甲基苯)磷酸

中文名称：: (1-氨基-甲基苯)磷酸

中文别名：: (1-氨基-甲基苯)磷酸;
α-Aminobenzylphosphonic acid C6H5CH(NH2)P(O)(OH)2

英文名称：: (1-Amino-1-phenylmethyl)phosphonic acid

英文别名：: 1-amino-1-phenylmethyl phosphonic acid;
H2NCHPhP(O)(OH)2;
(1-Amino-1-phenylmethyl)phosphonic acid;
(RS)-phosphonic acid;
(+/-)-1-aminophenylmethylphosphonic acid;
[amino(phenyl)methyl]phosphonic acid;
Phosphonic acid,(aminophenylmethyl);
(Aminophenylmethyl)phosphonic acid

CAS No.：: 18108-22-0

分子式：: C₇H₁₀NO₃P

分子量：: 187.13

精确分子量：: 187.04000

PSA：: 93.36000

MDL：: MFCD00014809

EINECS：: 226-260-7

InChI：: The Key: ZKFNOUUKULVDOB-UHFFFAOYSA-N3

风险术语：: R36/37/38

安全术语：: S26 S37/S39

分子结构式：

SDS：: 查看

(1-氨基-甲基苯)磷酸物化性质

密度：: 1.446g/cm3
沸点：: 407.9ºC at 760 mmHg
闪点：: 200.5ºC
蒸汽压：: 2.19E-07mmHg at 25°C
存储条件/存储方法：: 密闭于阴凉干燥环境中
稳定性相关：: 遵照规定使用和储存则不会分解。
其它信息：: 1.       性状：无可用

2.       密度（g/mL,25/4℃）：无可用

3.       相对蒸汽密度（g/mL,空气=1）：无可用

4.       熔点（ºC）：279-284

5.       沸点（ºC,常压）：无可用

6.       沸点（ºC,5.2kPa）：无可用

7.       折射率：无可用

8.       闪点（ºC）：无可用

9.       比旋光度（º）：无可用

10.    自燃点或引燃温度（ºC）：无可用

11.    蒸气压（kPa,25ºC）：无可用

12.    饱和蒸气压（kPa,60ºC）：无可用

13.    燃烧热（KJ/mol）：无可用

14.    临界温度（ºC）：无可用

15.    临界压力（KPa）：无可用

16.    油水（辛醇/水）分配系数的对数值：无可用

17.    爆炸上限（%,V/V）：无可用

18.    爆炸下限（%,V/V）：无可用

19.    溶解性：无可用

(1-氨基-甲基苯)磷酸毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SZ6562500

CHEMICAL NAME :: Phosphonic acid, (aminophenylmethyl)-

CAS REGISTRY NUMBER :: 18108-22-0

BEILSTEIN REFERENCE NO. :: 2049498

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H10-N-O3-P

MOLECULAR WEIGHT :: 187.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 38,435,1986

毒理学数据：

试验方法：腹腔
摄入剂量： “ 1毫克/千克
测试对象：啮齿动物-鼠
毒性类型：急性
毒性作用：详细的毒副作用没有报告以外的其他致死剂量值

生态数据：

该物质对环境可能有危害，对水体应给予特别注意。

(1-氨基-甲基苯)磷酸 MSDS

Name:	(1-Amino-1-phenylmethyl)phosphonic acid 97% Material Safety Data Sheet
Synonym:	alpha-Aminobenzylphosphonic aci
CAS:	18108-22-0

Section 1 - Chemical Product MSDS Name:(1-Amino-1-phenylmethyl)phosphonic acid 97% Material Safety Data Sheet
Synonym:alpha-Aminobenzylphosphonic aci

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
18108-22-0	(1-Amino-1-phenylmethyl)phosphonic aci	97%	unlisted

Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 18108-22-0: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 283 - 285 deg C (de
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density:
Molecular Formula: C7H10NO3P
Molecular Weight: 187.13

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of phosphorus, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 18108-22-0: SZ6562500 LD50/LC50:
Not available.
Carcinogenicity:
(1-Amino-1-phenylmethyl)phosphonic acid - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 18108-22-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 18108-22-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 18108-22-0 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

(1-氨基-甲基苯)磷酸分子结构与计算化学数据

分子结构数据

1、摩尔折射率：44.65

2、摩尔体积（m³/mol）：129.3

3、等张比容（90.2K）：377.3

4、表面张力（3.0 dyne/cm）：72.4

5、极化率（0.5 10^-24cm³）：17.70

计算化学数据

1.疏水参数计算参考值（XlogP）:-3.2

2.氢键供体数量:3

3.氢键受体数量:4

4.可旋转化学键数量:2

5.互变异构体数量:无

6.拓扑分子极性表面积83.6

7.重原子数量:12

8.表面电荷:0

9.复杂度:185

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:1

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

(1-氨基-甲基苯)磷酸上游产品

苯甲醛苯甲酰膦酸二乙酯 [(benzylamino)-phenylmethyl]phosphonic acid 苯甲醛苯甲酰膦酸二乙酯 [(benzylamino)-phenylmethyl]phosphonic acid

(1-氨基-甲基苯)磷酸下游产品

benzyl N-[diethoxyphosphoryl(phenyl)methyl]carbamate benzyl N-[diethoxyphosphoryl(phenyl)methyl]carbamate