盐酸美法仑
- 中文名称：
- 盐酸美法仑
- 中文别名：
- 左旋苯丙氨酸氮芥盐酸盐;
盐酸美法仑;
(S)-3-[4-[双(2-氯乙基)氨基]苯基]丙氨酸盐酸盐
- 英文名称：
- Melphalan hydrochloride
- 英文别名：
- Melphalan hydrochloride;
4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride;
Melphalan Hydrochloride,Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)
- CAS No.：
- 3223-07-2
- 分 子 式：
-
C13H19Cl3N2O2
- 分 子 量：
- 341.66100
- 精确分子量：
- 340.05100
- PSA：
- 66.56000
- InChI：
- InChI=1/C13H18Cl2N2O2.ClH/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19;/h1-4,12H,5-9,16H2,(H,18,19);1H/t12-;/m0./s13
- SDS：
- 查看
盐酸美法仑 物化性质
- 沸点：
- 473.1ºC at 760mmHg
- 闪点：
- 239.9ºC
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开存放
盐酸美法仑 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY4025000
- CHEMICAL NAME :
- Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-,
monohydrochloride, L-
- CAS REGISTRY NUMBER :
- 3223-07-2
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C13-H18-Cl2-N2-O2.Cl-H
- MOLECULAR WEIGHT :
- 341.69
- WISWESSER LINE NOTATION :
- QVYZ1R DN2G2G &GH -L
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 1200 ug/kg/5D-I
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting
- REFERENCE :
- CCROBU Cancer Chemotherapy Reports, Part 1. (Washington, DC) V.52(6)-59,
1968-75. For publisher information, see CTRRDO. Volume(issue)/page/year:
57,369,1973
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 430 ug/kg
- TOXIC EFFECTS :
- Blood - leukopenia
Blood - thrombocytopenia
Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5,
1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year:
2,201,1965
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 430 ug/kg
- TOXIC EFFECTS :
- Blood - leukopenia
Blood - agranulocytosis
Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5,
1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year:
2,201,1965
** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1300 ug/kg/4W
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60,
1940-78. For publisher information, see JJIND8. Volume(issue)/page/year:
36,915,1966
盐酸美法仑 海关数据
中国海关编码：2922499990
- 概述：
- 2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
- 监管条件：
- A.入境货物通关单B.出境货物通关单
- 检验检疫：
- P.进境动植物、动植物产品检疫Q.出境动植物、动植物产品检疫R.进口食品卫生监督检验S.出口食品卫生监督检验M.进口商品检验N.出口商品检验
- 摘要/Summary：
- HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
推荐供应商
湖北鑫红利化工有限公司
左旋苯丙氨酸氮芥盐酸盐
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- Cas号：3223-07-2
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