双(三乙基锡)硫酸酯
- 中文名称:
- 双(三乙基锡)硫酸酯
- 中文别名:
- 双(三乙基锡)硫酸酯;
硫酸三乙基锡
- 英文名称:
- BIS(TRIETHYLTIN)SULFATE
- 英文别名:
- bis(triethylstannyl) sulfate;
Bis-triethylstannyl sulfate;
Triethylstannium hydrogen sulfate;
EINECS 200-335-4;
Triethylhydroxytin sulfate;
4,6-Dioxa-5-thia-3,7-distannanonane,3,3,7,7-tetraethyl-,5,5-dioxide;
Triethyltin sulphate;
Tin,triethyl-,sulphate;
3,3,7,7-Tetraethyl-4,6-dioxa-5-thia-3,7-distannanonane 5,5-dioxide
- CAS No.:
- 57-52-3
- 分 子 式:
-
C12H30O4SSn2
- 分 子 量:
- 507.85
- 精确分子量:
- 509.99100
- PSA:
- 60.98000
- MDL:
- MFCD00048509
- EINECS:
- 200-335-4
- InChI:
- The Key: BTVURVLQSDTSSS-UHFFFAOYSA-L3
- 风险术语:
- R36/37/38
- SDS:
- 查看
双(三乙基锡)硫酸酯 物化性质
- 熔点:
- >300°C
- 存储条件/存储方法:
- 库房通风低温干燥,与氧化剂、酸类、食品添加剂分开存放
双(三乙基锡)硫酸酯 安全信息
- 包装等级:
- III
- 风险类别:
- 6.1
- 危险类别码:
- R36/37/38:Irritating to eyes, respiratory system and skin .
- 安全说明:
- S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
- RTECS号:
- PC4995000
- 安全标志:
- S26:万一接触眼睛,立即使用大量清水冲洗并送医诊治。
S45:出现意外或者感到不适,立刻到医生那里寻求帮助(最好带去产品容器标签)。
S60:本物质残余物和容器必须作为危险废物处理。
S61:避免排放到环境中。参考专门的说明/安全数据表。
双(三乙基锡)硫酸酯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XQ7175000
- CHEMICAL NAME :
- Tin, triethyl-, sulphate
- CAS REGISTRY NUMBER :
- 57-52-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 37
- MOLECULAR FORMULA :
- C12-H30-O4-S-Sn2
- MOLECULAR WEIGHT :
- 507.86
- WISWESSER LINE NOTATION :
- QSWO-SN-2&2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness
Lungs, Thorax, or Respiration - respiratory depression
Vascular - regional or general arteriolar or venous dilation
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 10,16,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5700 ug/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness
Lungs, Thorax, or Respiration - respiratory depression
Vascular - regional or general arteriolar or venous dilation
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 10,16,1955
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness
Lungs, Thorax, or Respiration - respiratory depression
Vascular - regional or general arteriolar or venous dilation
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 10,16,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9050 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 242,370,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - meningeal changes
Behavioral - muscle weakness
Behavioral - coma
- REFERENCE :
- BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce
Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year:
61,406,1955
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Vascular - regional or general arteriolar or venous dilation
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 10,16,1955
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 10,16,1955
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Vascular - regional or general arteriolar or venous dilation
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 10,16,1955
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 10,16,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Behavioral - muscle weakness
Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- BJIMAG British Journal of Industrial Medicine. (British Medical Journal,
Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year:
23,222,1966
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Bird - domestic
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 10,16,1955
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 57500 ug/kg/23D-C
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Musculoskeletal - other changes
- REFERENCE :
- JNENAD Journal of Neuropathology and Experimental Neurology. (American
Association of Neuropathologists, Inc., 1041 New Hapshire St., Lawrence, KS
66044) V.1- 1942- Volume(issue)/page/year: 35,1,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6 mg/kg/6D-I
- REFERENCE :
- JNENAD Journal of Neuropathology and Experimental Neurology. (American
Association of Neuropathologists, Inc., 1041 New Hapshire St., Lawrence, KS
66044) V.1- 1942- Volume(issue)/page/year: 25,202,1966
*** REVIEWS ***
ACGIH TLV-TWA 0.1 mg(Sn)/m3;STEL 0.2 mg/m3 (skin)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-Not classifiable as a human carcinogen
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
TOXICOLOGY REVIEW
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing
Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
Volume(issue)/page/year: 4,61,1973
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 0.1 mg(Sn)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,258,1971
OSHA PEL (Gen Indu):8H TWA 0.1 mg(Sn)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 0.1 mg(Sn)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 0.1 mg(Sn)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 0.1 mg(Sn)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 0.1 mg(Sn)/m3;Skin JAN 1993
OEL-BELGIUM:TWA 0.1 mg(Sn)/m3;Skin JAN 1993
OEL-DENMARK:TWA 0.1 mg(Sn)/m3;Skin JAN 1993
OEL-FINLAND:TWA 0.1 mg(Sn)/m3;STEL 0.3 mg(Sn)/m3;Skin JAN 1993
OEL-FRANCE:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3 JAN 1993
OEL-GERMANY:TWA 0.1 mg(Sn)/m3;Skin JAN 1993
OEL-HUNGARY:STEL 0.1 mg(Sn)/m3;Skin JAN 1993
OEL-THE NETHERLANDS:TWA 0.1 mg(Sn)/m3;Skin JAN 1993
OEL-THE PHILIPPINES:TWA 0.1 mg(Sn)/m3 JAN 1993
OEL-SWEDEN:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993
OEL-SWITZERLAND:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993
OEL-THAILAND:TWA 0.1 mg(Sn)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO ORGANOTIN COMPOUND-air:10H TWA 0.1 mg(Sn)/m3
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
双(三乙基锡)硫酸酯 分子结构与计算化学数据
计算化学数据
1.疏水参数计算参考值(XlogP):无
2.氢键供体数量:0
3.氢键受体数量:4
4.可旋转化学键数量:10
5.互变异构体数量:无
6.拓扑分子极性表面积61
7.重原子数量:19
8.表面电荷:0
9.复杂度:299
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:1