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Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
  Product identifiers
    : Tolylene-α,4-diisocyanate
    Product name
    CAS-No.        : 99741-73-8    
  

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Section 2. HAZARDS IDENTIFICATION
  Classification of the substance or mixture
  Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
    Acute toxicity, Inhalation (Category 2)
    Skin irritation (Category 2)
    Eye irritation (Category 2)
    Skin sensitization (Category 1)
    Carcinogenicity (Category 2)
    Specific target organ toxicity - single exposure (Category 3)
  Classification according to EU Directives 67/548/EEC or 1999/45/EC
    Very toxic by inhalation. Irritating to eyes, respiratory system and skin. May cause sensitization by
    inhalation and skin contact. Harmful to aquatic organisms, may cause long-term adverse effects in the
    aquatic environment. Limited evidence of a carcinogenic effect.
  Label elements
  Labelling according Regulation (EC) No 1272/2008 [CLP]
    Pictogram
    Signal word        Danger    
    Hazard statement(s)
    Causes skin irritation.
    May cause an allergic skin reaction.
    Causes serious eye irritation.
    Fatal if inhaled.
    May cause respiratory irritation.
    Suspected of causing cancer.
    Precautionary statement(s)
    Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
    Wear protective gloves.
    Wear respiratory protection.
    P305 + P351 + P338        IF IN EYES: Rinse cautiously with water for several minutes. Remove    
    contact lenses, if present and easy to do. Continue rinsing.
    Immediately call a POISON CENTER or doctor/ physician.
    Supplemental Hazard        none    
    Statements
  According to European Directive 67/548/EEC as amended.
    Hazard symbol(s)
    R-phrase(s)
    R26        Very toxic by inhalation.    
    R36/37/38        Irritating to eyes, respiratory system and skin.    
    R42/43        May cause sensitization by inhalation and skin contact.    
    R52/53        Harmful to aquatic organisms, may cause long-term adverse effects in    
    the aquatic environment.
    R40        Limited evidence of a carcinogenic effect.    
    S-phrase(s)
    S23        Do not breathe vapour.    
    S36/37        Wear suitable protective clothing and gloves.    
    S45        In case of accident or if you feel unwell, seek medical advice immediately    
    (show the label where possible).
    S61        Avoid release to the environment. Refer to special instructions/ Safety    
    data sheets.
  Other hazards
    Lachrymator.

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
  Substances
    Formula        : C9H6N2O2    
    Molecular Weight        : 174,16 g/mol    
    Component        Concentration    
  Tolylene-α ,4-diisocyanate
    CAS-No.        99741-73-8        -    

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Section 4. FIRST AID MEASURES
  Description of first aid measures
  General advice
    Consult a physician. Show this safety data sheet to the doctor in attendance.
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  In case of skin contact
    Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
  In case of eye contact
    Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
  If swallowed
    Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
  Most important symptoms and effects, both acute and delayed
    burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, spasm,
    inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis,
    pulmonary edema
  Indication of any immediate medical attention and special treatment needed
    no data available

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Section 5. FIREFIGHTING MEASURES
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Carbon oxides, nitrogen oxides (NOx)
  Advice for firefighters
    Wear self contained breathing apparatus for fire fighting if necessary.
  Further information
    no data available

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Section 6. ACCIDENTAL RELEASE MEASURES
  Personal precautions, protective equipment and emergency procedures
    Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate
    personnel to safe areas.
  Environmental precautions
    Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
    environment must be avoided.
  Methods and materials for containment and cleaning up
    Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
    containers for disposal.
  Reference to other sections
    For disposal see section 13.

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Section 7. HANDLING AND STORAGE
  Precautions for safe handling
    Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
    Normal measures for preventive fire protection.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
    opened must be carefully resealed and kept upright to prevent leakage.
    Recommended storage temperature: 2 - 8 °C
  Specific end uses
    no data available

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Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
    the product.
  Personal protective equipment
  Eye/face protection
    Face shield and safety glasses Use equipment for eye protection tested and approved under
    appropriate government standards such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    Complete suit protecting against chemicals, The type of protective equipment must be selected
    according to the concentration and amount of the dangerous substance at the specific workplace.
  Respiratory protection
    Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
    with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
    to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
    respirator. Use respirators and components tested and approved under appropriate government
    standards such as NIOSH (US) or CEN (EU).

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  Information on basic physical and chemical properties
    a) Appearance        Form: clear, liquid    
    Colour: colourless
    b) Odour        no data available    
    c) Odour Threshold        no data available    
    d) pH        no data available    
    e) Melting point/freezing        Melting point/range: 20 °C    
    point
    f) Initial boiling point and 152 °C at 25 hPa
    boiling range
    g) Flash point        110 °C - closed cup    
    h) Evaporation rate        no data available    
    i) Flammability (solid, gas) no data available
    j) Upper/lower        Lower explosion limit: 9 %(V)    
    flammability or
    explosive limits
    k) Vapour pressure        0,04 hPa at 25 °C    
    l) Vapour density        6,01 - (Air = 1.0)    
    m) Relative density        1,226 g/cm31,218 g/cm3    
    n) Water solubility        no data available    
    o) Partition coefficient: n-        no data available    
    octanol/water
    p) Autoignition        no data available    
    temperature
    q) Decomposition        no data available    
    temperature
    r) Viscosity        no data available    
    s) Explosive properties        no data available    
    t) Oxidizing properties        no data available    
  Other safety information
    no data available

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Section 10. STABILITY AND REACTIVITY
  Reactivity
    no data available
  Chemical stability
    no data available
  Possibility of hazardous reactions
    no data available
  Conditions to avoid
    Heat.
  Incompatible materials
    Strong oxidizing agentsAlcohols, Strong bases, Amines, acids, Strong oxidizing agents
  Hazardous decomposition products
    Other decomposition products - no data available

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Section 11. TOXICOLOGICAL INFORMATION
  Information on toxicological effects
  Acute toxicity
    no data available
  Skin corrosion/irritation
    no data available
  Serious eye damage/eye irritation
    no data available
  Respiratory or skin sensitization
    May cause allergic skin reaction.
  Germ cell mutagenicity
    no data available
  Carcinogenicity
    Limited evidence of carcinogenicity in animal studies
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as    
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    no data available
  Specific target organ toxicity - single exposure
    Inhalation - May cause respiratory irritation.
  Specific target organ toxicity - repeated exposure
    no data available
  Aspiration hazard
    no data available
  Potential health effects
  Inhalation        May be fatal if inhaled. Causes respiratory tract irritation.    
  Ingestion        May be harmful if swallowed.    
  Skin        May be harmful if absorbed through skin. Causes skin irritation.    
  Eyes        Causes serious eye irritation.    
  Signs and Symptoms of Exposure
    burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, spasm,
    inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis,
    pulmonary edema
  Additional Information
    RTECS: Not available

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Section 12. ECOLOGICAL INFORMATION
  Toxicity
    no data available
  Persistence and degradability
    no data available
  Bioaccumulative potential
    no data available
  Mobility in soil
    no data available
  Results of PBT and vPvB assessment
    no data available
  Other adverse effects
    Harmful to aquatic life.

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Section 13. DISPOSAL CONSIDERATIONS
  Waste treatment methods
  Product
    Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed
    professional waste disposal service to dispose of this material.
  Contaminated packaging
    Dispose of as unused product.

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Section 14. TRANSPORT INFORMATION
  UN number
    ADR/RID: 2078        IMDG: 2078        IATA: 2078    
  UN proper shipping name
    ADR/RID: TOLUENE DIISOCYANATE
    IMDG: TOLUENE DIISOCYANATE
    IATA:        Toluene diisocyanate    
  Transport hazard class(es)
    ADR/RID: 6.1        IMDG: 6.1        IATA: 6.1    
  Packaging group
    ADR/RID: II        IMDG: II        IATA: II    
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no    
  Special precautions for user
    no data available

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Section 15. REGULATORY INFORMATION
    This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
  Safety, health and environmental regulations/legislation specific for the substance or mixture
    no data available
  Chemical Safety Assessment

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SECTION 16 - ADDITIONAL INFORMATION
N/A