双(3,4-二氯苯基)二氮烯-1-氧化物
- 中文名称：
- 双(3,4-二氯苯基)二氮烯-1-氧化物
- 中文别名：
- 双(3,4-二氯苯基)二氮烯-1-氧化物;
3,3',4,4'-四氯偶氮氧苯
- 英文名称：
- 3,3,4,4-TETRACHLOROAZOXYBENZENE
- 英文别名：
- (3,4-dichlorophenyl)-(3,4-dichlorophenyl)imino-oxidoazanium;
Diazene,bis(3,4-dichlorophenyl)-,1-oxide;
3,3',4,4'-tetrachloroazoxybenzole;
TCAOB;
bis-(3,4-dichloro-phenyl)-diazene-N-oxide;
Azoxybenzene,3,3',4,4'-tetrachloro;
3,3',4,4'-Tetrachlor-azoxybenzol;
3,3',4,4'-TETRACHLOROAZOXYBENZENE;
Bis-(3,4-dichlor-phenyl)-diazen-N-oxid;
Bis(3,4-dichlorophenyl)diazene 1-oxide;
3,4,3',4'-Tetrachloroazoxybenzene;
3,4,3',4'-Tetrachlor-azoxybenzol
- CAS No.：
- 21232-47-3
- 分 子 式：
-
C12H6Cl4N2O
- 分 子 量：
- 336.00084
- 精确分子量：
- 333.92300
- PSA：
- 41.11000
- InChI：
- The Key: BCOVXBPXQLIGEV-ISLYRVAYSA-N3
- SDS：
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双(3,4-二氯苯基)二氮烯-1-氧化物 物化性质
- 密度：
- 1.53g/cm3
- 沸点：
- 472.7ºC at 760 mmHg
- 闪点：
- 239.7ºC
- 折射率：
- 1.641
- 蒸汽压：
- 1.19E-08mmHg at 25°C
双(3,4-二氯苯基)二氮烯-1-氧化物 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CO4150000
- CHEMICAL NAME :
- Azoxybenzene, 3,3',4,4'-tetrachloro-
- CAS REGISTRY NUMBER :
- 21232-47-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C12-H6-Cl4-N2-O
- MOLECULAR WEIGHT :
- 336.00
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg/17W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight
Blood - changes in erythrocyte (RBC) count
Related to Chronic Data - changes in testicular weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 650 mg/kg/13W-I
- TOXIC EFFECTS :
- Behavioral - food intake (animal)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 350 mg/kg/48D-I
- TOXIC EFFECTS :
- Liver - other changes
Endocrine - changes in thymus weight
Related to Chronic Data - changes in testicular weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg/28D-I
- TOXIC EFFECTS :
- Liver - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - transaminases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 75600 ug/kg
- SEX/DURATION :
- female 14 day(s) pre-mating - 28 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - blood and lymphatic
systems (including spleen and marrow)
Reproductive - Effects on Newborn - live birth index (measured after birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 7560 ug/kg
- SEX/DURATION :
- female 14 day(s) pre-mating - 28 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 16 mg/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 6 mg/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
Reproductive - Specific Developmental Abnormalities - urogenital system
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 134 mg/kg/4W (Continuous)
- REFERENCE :
- AECTCV Archives of Environmental Contamination and Toxicology.
(Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
070944) V.1- 1973- Volume(issue)/page/year: 14,677,1985
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