吗喹酮
- 中文名称：
- 吗喹酮
- 中文别名：
- 吗喹酮
- 英文名称：
- moquizone
- 英文别名：
- 1-(2-morpholin-4-ylacetyl)-3-phenyl-2H-quinazolin-4-one;
Moquizonum [INN-Latin];
Mochizone [DCIT];
1-Morpholinoacetyl-3-phenyl-4-oxo-1,2,3,4-tetrahydrochinazolin;
2,3-Dihydro-1-(morpholinoacetyl)-3-phenyl-4(1H)-quinazolinone;
1-(morpholin-4-yl-acetyl)-3-phenyl-2,3-dihydro-1H-quinazolin-4-one;
Moquizone [INN];
1-Morpholinomethylcarbonyl-3-phenyl-2,3-dihydro-4(1H)-chinazolinon;
EINECS 243-021-2;
Moquizone;
4(1H)-Quinazolinone,2,3-dihydro-1-(morpholinoacetyl)-3-phenyl;
Moquizona [INN-Spanish];
4(1H)-Quinazolinone,2,3-dihydro-1-(4-morpholinyacetyl)-3-phenyl
- CAS No.：
- 19395-58-5
- 分 子 式：
-
C20H21N3O3
- 分 子 量：
- 351.404
- 精确分子量：
- 351.15800
- PSA：
- 53.09000
- EINECS：
- 243-021-2
- SDS：
- 查看
吗喹酮 物化性质
- 密度：
- 1.278g/cm3
- 沸点：
- 599.9ºC at 760 mmHg
- 闪点：
- 316.6ºC
- 折射率：
- 1.618
- 蒸汽压：
- 2.37E-14mmHg at 25°C
吗喹酮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VA3150000
- CHEMICAL NAME :
- 4(1H)-Quinazolinone,
2,3-dihydro-1-(morpholinoacetyl)-3-phenyl-
- CAS REGISTRY NUMBER :
- 19395-58-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C20-H21-N3-O3
- MOLECULAR WEIGHT :
- 351.44
- WISWESSER LINE NOTATION :
- T66 BVN EN DHJ CR& EV1- AT6N DOTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2220 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis
Vascular - regional or general arteriolar or venous dilation
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
16,571,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 146 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
16,571,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 930 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation
Lungs, Thorax, or Respiration - respiratory stimulation
Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc.,
c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
606, Japan) V.1- 1951- Volume(issue)/page/year: 22,235,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 559 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
16,571,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 774 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
16,571,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 237 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
16,571,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1730 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis
Vascular - regional or general arteriolar or venous dilation
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
16,571,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
16,571,1970
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吗喹酮
- 联系人：许伟伟
- 电 话：0371-86259281
- 手 机：15981966935
- Cas号：19395-58-5
- 包装：洽谈
- 纯度：
- 价格：洽谈