桑霉素
- 中文名称：
- 桑霉素
- 中文别名：
- 桑霉素;
桑吉瓦霉素
- 英文名称：
- SANGIVAMYCIN
- 英文别名：
- sangivamycin;
7-Carboxamido-7-deazaadenosine;
7-DEAZA-7-CARBAMOYLADENOSINE;
7-DEAZAADENOSINE-7-CARBOXAMIDE;
SANGIVAMYCIN
- CAS No.：
- 18417-89-5
- 分 子 式：
-
C12H15N5O5
- 分 子 量：
- 309.28
- 精确分子量：
- 327.11800
- PSA：
- 178.97000
- InChI：
- The Key: OBZJZDHRXBKKTJ-UHFFFAOYSA-N3
- 风险术语：
- R26/27/28
- SDS：
- 查看
桑霉素 物化性质
- 沸点：
- 880.6ºC at 760 mmHg
- 闪点：
- 486.4ºC
- 蒸汽压：
- 3.3E-33mmHg at 25°C
桑霉素 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY9355000
- CHEMICAL NAME :
- 7H-Pyrrolo(2,3-d)pyrimidine-5-carboxamide,
4-amino-7-beta-D-ribofuranosyl-
- CAS REGISTRY NUMBER :
- 18417-89-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H15-N5-O5
- MOLECULAR WEIGHT :
- 309.32
- WISWESSER LINE NOTATION :
- T56 BN GN INJ FZ HVZ I- BT5OTJ CQ DQ E1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Cells - not otherwise specified
- DOSE/DURATION :
- 500 nmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
41,1784,1981