PEMOLINE 镁
- 中文名称：
- PEMOLINE 镁
- 中文别名：
- PEMOLINE 镁
- 英文名称：
- MAGNESIUM PEMOLINE
- 英文别名：
- magnesium,2-amino-5-phenyl-1,3-oxazol-4-one,dihydroxide;
Pemoline magnesium chelate;
2-Amino-5-phenyl-2-oxazolin-4-one + Mg(OH)2;
Magnesium pemoline;
Pemoline magnesium;
Pemoline magnesium hydroxide mixture;
Tamilan;
Pemoline magnesium hydroxide;
Pemolin and magnesium hydroxide;
DEA No. 1530
- CAS No.：
- 18968-99-5
- 分 子 式：
-
C9H10MgN2O4
- 分 子 量：
- 234.49
- 精确分子量：
- 234.04900
- PSA：
- 105.14000
- SDS：
- 查看
PEMOLINE 镁 物化性质
- 沸点：
- 313.6ºC at 760 mmHg
- 闪点：
- 143.4ºC
PEMOLINE 镁 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RY1105000
- CHEMICAL NAME :
- Pemoline magnesium
- CAS REGISTRY NUMBER :
- 18968-99-5
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C9-H10-Mg-N2-O4
- MOLECULAR WEIGHT :
- 234.52
- WISWESSER LINE NOTATION :
- T5OYMV EHJ BUM ER &-MG-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 149 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
Gastrointestinal - nausea or vomiting
- REFERENCE :
- CPEDAM Clinical Pediatrics (Philadelphia). (Lippincott/Harper, Journal
Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1962-
Volume(issue)/page/year: 18,761,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 485 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 23,810,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
Behavioral - irritability
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 181,441,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 487 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - changes in motor activity (specific assay)
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 181,441,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - changes in motor activity (specific assay)
Skin and Appendages - hair
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 181,441,1969