CHEMICAL IDENTIFICATION

RTECS NUMBER :

OL5975000

CHEMICAL NAME :

Lysol

CAS REGISTRY NUMBER :

12772-68-8

LAST UPDATED :

199712

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538621 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - woman

DOSE/DURATION :

5 gm/kg

TOXIC EFFECTS :

Vascular - relaxation (isolated tissues) Lungs, Thorax, or Respiration - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :

WILEAR Wiadomosci Lekarskie. Medical News. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1948- Volume(issue)/page/year: 27,1211,1974

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - woman

DOSE/DURATION :

5 gm/kg

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - urine volume decreased Nutritional and Gross Metabolic - metabolic acidosis

REFERENCE :

WILEAR Wiadomosci Lekarskie. Medical News. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1948- Volume(issue)/page/year: 27,1211,1974

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - woman

DOSE/DURATION :

2 gm/kg

TOXIC EFFECTS :

Behavioral - general anesthetic Behavioral - coma Gastrointestinal - other changes

REFERENCE :

BEGMA5 Beitraege zur Gerichtlichen Medizin. (Verlag Franz Deuticke, Helferstorferstr 4, A-1010 Vienna, Austria) V.1- 1911- Volume(issue)/page/year: 13,56,1935 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 43315 No. of Facilities: 12160 (estimated) No. of Industries: 55 No. of Occupations: 39 No. of Employees: 68587 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 43315 No. of Facilities: 1080 (estimated) No. of Industries: 17 No. of Occupations: 11 No. of Employees: 7802 (estimated) No. of Female Employees: 2922 (estimated)