呋替啶
- 中文名称：
- 呋替啶
- 中文别名：
- 呋替啶
- 英文名称：
- furethidine
- 英文别名：
- ethyl 1-[2-(oxolan-2-ylmethoxy)ethyl]-4-phenylpiperidine-4-carboxylate;
Furethidinum [INN-Latin];
Ethyl 4-phenyl-1-(2-tetrahydrofurfuryloxyethyl)piperidine-4-carboxylate;
4-Phenyl-4-ethoxycarbonyl-1-(2-tetrahydrofurfuryloxy-ethyl)-piperidin;
4-phenyl-1-(2-tetrahydrofurfuryloxy-ethyl)-piperidine-4-carboxylic acid ethyl ester;
1-(2-Tetrahydrofurfuryloxyethyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester;
EINECS 219-195-0;
furethidine;
Furethidine [INN:BAN:DCF];
Furetidina [DCIT];
Furethidinum;
DEA No. 9626
- CAS No.：
- 2385-81-1
- 分 子 式：
-
C21H31NO4
- 分 子 量：
- 0
- 精确分子量：
- 361.22500
- PSA：
- 48.00000
- InChI：
- The Key: NNCOZXNZFLUYGG-UHFFFAOYSA-N3
- SDS：
- 查看
呋替啶 物化性质
- 密度：
- 1.093g/cm3
- 沸点：
- 470.3ºC at 760mmHg
- 闪点：
- 238.2ºC
- 折射率：
- 1.519
- 蒸汽压：
- 5.11E-09mmHg at 25°C
呋替啶 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NS6210000
- CHEMICAL NAME :
- Isonipecotic acid,
4-phenyl-1-(2-((tetrahydrofurfuryl)oxy)ethyl)-, ethyl
ester
- CAS REGISTRY NUMBER :
- 2385-81-1
- BEILSTEIN REFERENCE NO. :
- 0496786
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H31-N-O4
- MOLECULAR WEIGHT :
- 361.53
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 135 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 15,254,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 15,254,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15500 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 15,254,1960